Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

271 questions · 287 findings · 26 reviews · Colorectal

No studies found 22 · 7.7%GRADE not reported 7 · 2.4%Very low 83 · 28.9%Low 115 · 40.1%Moderate 49 · 17.1%High 11 · 3.8%

Combined oral and intravenous vs oral or intravenous alone

Wound infection · colorectal surgery

Combined oral and intravenous leads to lower surgical wound infection: oral + iv versus iv alone compared with oral or intravenous alone (high certainty).

2 findings from 1 review

Intervention not reported

Overall five year survival ‐ Colorectal cancer · Patients with outcomes after colorectal cancer surgery

It is very uncertain whether the intervention changes overall five year survival ‐ Colorectal cancer (very low certainty).

1 finding from 1 review

Intervention not reported

Permanent stoma rate ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery

It is very uncertain whether the intervention changes permanent stoma rate ‐ Rectal cancer (very low certainty).

1 finding from 1 review

Intervention not reported

Abdominoperineal excision of the rectum rate ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery

It is very uncertain whether the intervention changes abdominoperineal excision of the rectum rate ‐ Rectal cancer (very low certainty).

1 finding from 1 review

Intervention not reported

Overall five year survival ‐ Colorectal cancer · Patients with outcomes after colorectal cancer surgery

The intervention may leads to lower overall five year survival ‐ Colorectal cancer (low certainty).

1 finding from 1 review

Intervention not reported

Overall five year survival ‐ Colon cancer · Patients with outcomes after colorectal cancer surgery

The intervention may leads to lower overall five year survival ‐ Colon cancer (low certainty).

1 finding from 1 review

Intervention not reported

Overall five year survival ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery

The intervention showed no clear difference in overall five year survival ‐ Rectal cancer (low certainty).

1 finding from 1 review

Intervention not reported

Five year disease specific survival ‐ Colorectal cancer · Patients with outcomes after colorectal cancer surgery

The intervention showed no clear difference in five year disease specific survival ‐ Colorectal cancer (low certainty).

1 finding from 1 review

Intervention not reported

Inpatient and 30 day mortality ‐ Colon cancer · Patients with outcomes after colorectal cancer surgery

It is very uncertain whether the intervention changes inpatient and 30 day mortality ‐ Colon cancer (very low certainty).

1 finding from 1 review

Intervention not reported

Inpatient and 30 day mortality ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery

The intervention showed no clear difference in inpatient and 30 day mortality ‐ Rectal cancer (low certainty).

1 finding from 1 review

Intervention not reported

Anastomotic leak rate ‐ Colon cancer · Patients with outcomes after colorectal cancer surgery

The intervention showed no clear difference in anastomotic leak rate ‐ Colon cancer (low certainty).

1 finding from 1 review

Intervention not reported

Anastomotic leak rate ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery

The intervention showed no clear difference in anastomotic leak rate ‐ Rectal cancer (low certainty).

1 finding from 1 review