Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

214 questions · 250 findings · 24 reviews

No studies found 50 · 20%GRADE not reported 112 · 44.8%Very low 42 · 16.8%Low 24 · 9.6%Moderate 17 · 6.8%High 5 · 2%

Atraumatic restorative treatment plus fluoride varnish vs Silver diamine fluoride plus fluoride varnish

Oral health-related quality of life · Children with dental caries

The direct estimate found no statistically significant difference in oral health-related quality of life between atraumatic restorative treatment plus fluoride varnish and silver diamine fluoride plus fluoride varnish.

2 findings from 1 review

Atraumatic restorative treatment vs Silver diamine fluoride

Oral health-related quality of life · Children with dental caries

The network estimate found no statistically significant difference in oral health-related quality of life between atraumatic restorative treatment and silver diamine fluoride.

2 findings from 1 review

SDF applied once (single application, no re-application) vs Other non/minimally-invasive treatment (ART or silver-fluoride varnish)

Caries arrest · Children (age 1-10 years) with active cavitated dentin caries lesions in primary molars

A single (one-time) SDF application did not significantly arrest caries (pooled ES -0.09, 95% CI -0.48 to 0.29; ungraded).

1 finding from 1 review

Hall technique vs Silver-modified atraumatic restorative treatment (SMART)

Treatment success (caries lesion arrest or restoration survival) · Children (aged 3-11 y) with cavitated caries lesions in primary teeth

At 12 months, the Hall technique had significantly higher treatment success than SMART (OR 4.36; moderate certainty).

2 findings from 1 review

Hall technique vs Silver diamine fluoride

Treatment success (caries lesion arrest or restoration survival) · Children (aged 3-11 y) with cavitated caries lesions in primary teeth

At 12 months, the Hall technique had significantly higher treatment success than SDF (OR 3.23; moderate certainty).

2 findings from 1 review

Honey vs silver sulfadiazine

Negative wound swab · people with burns

It is very uncertain whether honey changes negative wound swab compared with silver sulfadiazine (very low certainty).

1 finding from 1 review