Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

318 questions · 353 findings · 50 reviews

No studies found 31 · 8.8%GRADE not reported 53 · 15%Very low 99 · 28%Low 95 · 26.9%Moderate 68 · 19.3%High 7 · 2%

Intervention vs control

Selective bowel decontamination versus prebiotics · people undergoing liver transplantation
2 findings from 1 review

Intervention not reported

Utilisation of research (Thailand) (for six obstetric practices: social support during labour, magnesium sulphate for eclampsia, corticosteroids to women with preterm birth, selective episiotomy, antibiotic use at caesarean section and vacuum extr... · Healthcare decision makers, health system managers or policy makers
1 finding from 1 review

Intervention not reported

Utilisation of research (Mexico) (for six obstetric practices: social support during labour, magnesium sulphate for eclampsia, corticosteroids to women with preterm birth, selective episiotomy, antibiotic use at caesarean section and vacuum extrac... · Healthcare decision makers, health system managers or policy makers
1 finding from 1 review

Carvedilol vs beta‐blocker

Upper gastrointestinal bleeding · adults with cirrhosis and gastroesophageal varices

It is very uncertain whether carvedilol changes upper gastrointestinal bleeding compared with traditional, non‐selective beta‐blockers (very low certainty).

1 finding from 1 review

Carvedilol vs beta‐blocker

Non‐serious adverse events · adults with cirrhosis and gastroesophageal varices

It is very uncertain whether carvedilol changes non‐serious adverse events compared with traditional, non‐selective beta‐blockers (very low certainty).

1 finding from 1 review

Carvedilol vs beta‐blocker

Haemodynamic treatment failure · adults with cirrhosis and gastroesophageal varices

It is very uncertain whether carvedilol changes haemodynamic treatment failure compared with traditional, non‐selective beta‐blockers (very low certainty).

1 finding from 1 review

Routine invasive strategies vs selective invasive strategies (conservative)

Death · participants with UA/NSTEMI in the stent era

Routine invasive strategies showed no clear difference in death compared with selective invasive strategies (conservative) (low certainty).

1 finding from 1 review

Routine invasive strategies vs selective invasive strategies (conservative)

Myocardial infarction · participants with UA/NSTEMI in the stent era

Routine invasive strategies showed no clear difference in myocardial infarction compared with selective invasive strategies (conservative) (moderate certainty).

1 finding from 1 review

Routine invasive strategies vs selective invasive strategies (conservative)

Fatal or nonfatal myocardial infarction · participants with UA/NSTEMI in the stent era

Routine invasive strategies showed no clear difference in death or non‐fatal Myocardial infarction compared with selective invasive strategies (conservative) (low certainty).

1 finding from 1 review

Routine invasive strategies vs selective invasive strategies (conservative)

Refractory angina · participants with UA/NSTEMI in the stent era

Routine invasive strategies probably leads to lower refractory angina compared with selective invasive strategies (conservative) (moderate certainty).

1 finding from 1 review

Routine invasive strategies vs selective invasive strategies (conservative)

Patient readmissions · participants with UA/NSTEMI in the stent era

Routine invasive strategies probably leads to lower rehospitalisation compared with selective invasive strategies (conservative) (moderate certainty).

1 finding from 1 review

Routine invasive strategies vs selective invasive strategies (conservative)

Complications of angiography or revascularization Bleeding · participants with UA/NSTEMI in the stent era

Routine invasive strategies probably leads to higher complications of angiography or revascularization Bleeding compared with selective invasive strategies (conservative) (moderate certainty).

1 finding from 1 review

Routine invasive strategies vs selective invasive strategies (conservative)

Complications of angiography or revascularization Procedure‐related myocardial infarction · participants with UA/NSTEMI in the stent era

Routine invasive strategies probably leads to higher complications of angiography or revascularization Procedure‐related… compared with selective invasive strategies (conservative) (moderate certainty).

1 finding from 1 review

Prophylactic vs selective blood transfusion

Severe maternal morbidity (congestive cardiac failure) · patients with sickle cell disease in pregnancy

It is very uncertain whether prophylactic changes severe maternal morbidity (congestive cardiac failure) compared with selective blood transfusion (very low certainty).

1 finding from 1 review