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Evidence found and GRADE certainty

480 questions · 494 findings · 38 reviews

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No studies found 118 · 23.9%GRADE not reported 54 · 10.9%Very low 176 · 35.6%Low 99 · 20%Moderate 34 · 6.9%High 13 · 2.6%

Propofol vs sevoflurane

Adverse event ‐ haemodynamic changes, number of events · patients with rapid emergence from anaesthesia after undergoing brain tumour surgery

Propofol may leads to higher adverse event ‐ haemodynamic changes, number of events compared with sevoflurane (low certainty).

1 finding from 1 review

Propofol vs sevoflurane

Adverse event ‐ pain, visual analogue scale · patients with rapid emergence from anaesthesia after undergoing brain tumour surgery

Propofol showed no clear difference in adverse event ‐ pain, visual analogue scale compared with sevoflurane (low certainty).

1 finding from 1 review

Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with the intent to rapidly extubate (InSurE)

Death or bronchopulmonary dysplasia · preterm infants with or at risk of respiratory distress syndrome

Surfactant administration via laryngeal mask airway (S‐LMA) showed no clear difference in death or bronchopulmonary dysplasia compared with surfactant administration via endotracheal tube (ETT) with the… (low certainty).

1 finding from 1 review

Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with the intent to rapidly extubate (InSurE)

Need for mechanical ventilation · preterm infants with or at risk of respiratory distress syndrome

Surfactant administration via laryngeal mask airway (S‐LMA) may leads to lower mechanical ventilation at any time Any time to discharge compared with surfactant administration via endotracheal tube (ETT) with the… (low certainty).

1 finding from 1 review

Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with the intent to rapidly extubate (InSurE)

Pulmonary air leak · preterm infants with or at risk of respiratory distress syndrome

Surfactant administration via laryngeal mask airway (S‐LMA) showed no clear difference in pulmonary air leak, any (during first hospitalisation) Anytime to… compared with surfactant administration via endotracheal tube (ETT) with the… (low certainty).

1 finding from 1 review

Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with the intent to rapidly extubate (InSurE)

Bronchopulmonary dysplasia · preterm infants with or at risk of respiratory distress syndrome

Surfactant administration via laryngeal mask airway (S‐LMA) showed no clear difference in bronchopulmonary dysplasia (clinical definition) among survivors compared with surfactant administration via endotracheal tube (ETT) with the… (low certainty).

1 finding from 1 review

Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with the intent to rapidly extubate (InSurE)

Intraventricular haemorrhage, Papile grade 3/4 · preterm infants with or at risk of respiratory distress syndrome
1 finding from 1 review

Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with the intent to rapidly extubate (InSurE)

Mortality before hospital discharge · preterm infants with or at risk of respiratory distress syndrome

Surfactant administration via laryngeal mask airway (S‐LMA) showed no clear difference in death (all causes) during the first hospitalisation Anytime to… compared with surfactant administration via endotracheal tube (ETT) with the… (low certainty).

1 finding from 1 review

Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with the intent to rapidly extubate (InSurE)

Neurosensory disability in survivors · preterm infants with or at risk of respiratory distress syndrome

The review found no eligible studies for this question.

1 finding from 1 review