Question · asked by 1 review

Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with the intent to rapidly extubate (InSurE): Need for mechanical ventilation

Surfactant administration via laryngeal mask airway (S‐LMA) may leads to lower mechanical ventilation at any time Any time to discharge compared with surfactant administration via endotracheal tube (ETT) with the… (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with the intent to rapidly extubate (InSurE)
Mechanical ventilation at any time Any time to discharge · preterm infants with or at risk of respiratory distress syndrome
Surfactant administration via laryngeal mask airway (S‐LMA) may leads to lower mechanical ventilation at any time Any time to discharge compared with surfactant administration via endotracheal tube (ETT) with the… (low certainty).
Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants… (2024) · Cochrane Headline outcomes only
RR 0.53 [0.36, 0.78]5 studies · 333 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants with or at risk of…
2024 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.