Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

151 questions · 153 findings · 18 reviews

No studies found 19 · 12.4%GRADE not reported 18 · 11.8%Very low 26 · 17%Low 57 · 37.3%Moderate 27 · 17.6%High 6 · 3.9%

Intervention not reported

Mortality at end of scheduled · people with acute TBI secondary to head injury

The intervention showed no clear difference in mortality at end of scheduled (low certainty).

1 finding from 1 review

Intervention not reported

Disability (unfavourable outcomes: death, vegetative state, severe disability; GOS 1‐3) at end of scheduled · people with acute TBI secondary to head injury

The intervention showed no clear difference in disability (unfavourable outcomes: death, vegetative state, severe… (moderate certainty).

1 finding from 1 review

Intervention not reported

Intracranial pressure (ICP) within the treatment period · people with acute TBI secondary to head injury
1 finding from 1 review

Intervention not reported

Blood pressure · people with acute TBI secondary to head injury
1 finding from 1 review

Intervention not reported

Body temperature · people with acute TBI secondary to head injury
1 finding from 1 review

Intervention not reported

Adverse events · people with acute TBI secondary to head injury
1 finding from 1 review