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What do systematic reviews say?

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Evidence found and GRADE certainty

216 questions · 226 findings · 24 reviews · Metabolic and Endocrine Disorders

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No studies found 84 · 37.2%GRADE not reported 5 · 2.2%Very low 73 · 32.3%Low 39 · 17.3%Moderate 25 · 11.1%High 0 · 0%

Adverse event outcomes for dietary combined with physical activity interventions vs usual care

All‐cause mortality · people at increased risk for developing type 2 diabetes

It is very uncertain whether diet plus physical activity changes all‐cause mortality compared with standard treatment (very low certainty).

1 finding from 1 review

Adverse event outcomes for dietary combined with physical activity interventions vs usual care

Development of type 2 diabetes · people at increased risk for developing type 2 diabetes

Diet plus physical activity probably leads to lower incidence of type 2 diabetes mellitus Diagnostic criteria: 3 trials… compared with standard treatment (moderate certainty).

1 finding from 1 review

Adverse event outcomes for dietary combined with physical activity interventions vs usual care

Cardiovascular mortality · people at increased risk for developing type 2 diabetes

It is very uncertain whether diet plus physical activity changes cardiovascular mortality compared with standard treatment (very low certainty).

1 finding from 1 review