Signs or symptoms of pulpal disease · Patients with carious teeth, affecting any tooth surface(s), in unrestored primary and permanent teeth
No dentinal caries removal (caries sealed under a preformed metal… showed no clear difference in signs or symptoms of pulpal disease compared with complete caries removal (moderate certainty).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Permanent teeth with carious pulp exposure
In partial pulpotomy, MTA had significantly higher success than calcium hydroxide (OR 2.81; ungraded).
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Postoperative pain (patient-reported) · Vital permanent teeth (mature or immature) with deep or extremely deep caries and asymptomatic pulp or reversible pulpitis, undergoing…
The effect of material choice (MTA vs CaOH) on postoperative pain is unclear: two small studies used different methods and reported contradictory results, so no meta-analysis was performed (ungraded).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Vital permanent teeth (mature or immature) with deep or extremely deep caries and asymptomatic pulp or reversible pulpitis, undergoing…
At 36-month follow-up, HCSC show higher odds of clinical and radiographic success than CaOH (OR 2.34, 95% CI 1.43 to 3.84; ungraded subgroup).
3 findings from 1 review
OR 2.34 [1.43, 3.84]
2 studies · 379 participants
GRADE not reported
OR 4.44 [1.63, 12.07]
3 studies · 174 participants
GRADE not reported
OR 2.68 [1.7, 4.22]
5 studies · 552 participants
Moderate
Overall success (composite of clinical and radiographic success) · Vital permanent teeth (mature or immature) with deep or extremely deep caries and asymptomatic pulp or reversible pulpitis, undergoing…
Biodentine and calcium hydroxide did not differ significantly in clinical and radiographic success (OR 3.14, 95% CI 0.91 to 10.86; ungraded subgroup analysis).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Vital permanent teeth (mature or immature) with deep or extremely deep caries and asymptomatic pulp or reversible pulpitis, undergoing…
Mineral trioxide aggregate shows higher odds of clinical and radiographic success than calcium hydroxide (OR 3.05, 95% CI 1.70 to 5.45; ungraded subgroup analysis).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Permanent teeth with carious pulp exposure
Biodentine may increase pulpotomy success versus calcium hydroxide at marginal significance (ungraded).
1 finding from 1 review
OR 6.03 [0.97, 37.6]
2 studies
GRADE not reported
Overall success (composite of clinical and radiographic success) · Permanent teeth with carious pulp exposure
MTA and Biodentine have similar pulpotomy success (OR 0.89, not significant; low certainty).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Permanent teeth with carious pulp exposure
MTA and TotalFill BC had comparable pulpotomy success (ungraded).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Mature permanent teeth with irreversible pulpitis and carious pulp exposure (treated with full pulpotomy)
Platelet-rich fibrin and calcium hydroxide showed no significant difference in success (ungraded; effect size not reported).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Permanent teeth with carious pulp exposure
MTA and calcium-enriched mixture had comparable pulpotomy success (ungraded).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Permanent teeth with carious pulp exposure
MTA and platelet-rich fibrin had comparable pulpotomy success (ungraded).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth undergoing pulpotomy
The effect of MTA versus CH after pulpotomy is uncertain (low certainty).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in immature permanent teeth undergoing pulpotomy
The two trials of PRF versus MTA for success gave contradictory results and were not pooled (ungraded).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth undergoing pulpotomy
MTA and CEM performed comparably for clinical and radiographic success (2 RCTs, not pooled; ungraded).
1 finding from 1 review
Dentin bridge formation · Patients with carious pulp exposure in permanent teeth undergoing partial pulpotomy
Evidence on dentin bridge formation for calcium hydroxide versus MTA is weak and imprecise, with no material shown superior (4 RCTs, not pooled; ungraded).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in immature permanent teeth
In immature teeth, the effect of MTA versus calcium hydroxide on success is very uncertain (OR 2.22, 95% CI 0.13-36.67; very low certainty).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth undergoing direct pulp capping
For direct pulp capping, MTA probably achieves higher clinical and radiographic success than calcium hydroxide (OR 3.10, 95% CI 1.66-5.79; moderate certainty).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth of mixed/unspecified root maturation
In mixed-maturation teeth, the effect of MTA versus calcium hydroxide on success is very uncertain (OR 1.11, 95% CI 0.17-7.11; very low certainty).
1 finding from 1 review
Tooth discoloration · Patients with carious pulp exposure in permanent teeth undergoing DPC or pulpotomy
More tooth discoloration was observed with MTA than with Biodentine, but odds ratios were implausibly large and not pooled (3 RCTs; ungraded).
1 finding from 1 review