Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,340 questions · 1,512 findings · 205 reviews

No studies found 317 · 21%GRADE not reported 358 · 23.7%Very low 356 · 23.5%Low 271 · 17.9%Moderate 173 · 11.4%High 37 · 2.4%

Zuclopenthixol dihydrochloride vs OTHER ANTIPSYCHOTIC: f. PERPHENAZINE

Adverse effects: Clinically important general adverse effect (EPSEs requiring medication ‐ medium term) · schizophrenia

It is very uncertain whether zuclopenthixol dihydrochloride changes adverse effects: Clinically important general adverse effect (EPSEs… compared with perphenazine (very low certainty).

1 finding from 1 review

Zuclopenthixol dihydrochloride vs RISPERIDONE

Adverse effects: Clinically important general adverse effect ‐ short term (EPSEs requiring medication) · schizophrenia

It is very uncertain whether zuclopenthixol dihydrochloride changes adverse effects: Clinically important general adverse effect ‐ short… compared with risperidone (very low certainty).

1 finding from 1 review

Zuclopenthixol dihydrochloride vs sulpiride

Global state: Average endpoint global state score (clinically improved) (CGI ‐ unchanged/worse) · schizophrenia

It is very uncertain whether zuclopenthixol dihydrochloride changes global state: Average endpoint global state score (clinically… compared with sulpiride (very low certainty).

1 finding from 1 review

Zuclopenthixol dihydrochloride vs sulpiride

Adverse effects: Clinically important general adverse effect ‐ requiring hypnotics/sedatives · schizophrenia

It is very uncertain whether zuclopenthixol dihydrochloride changes adverse effects: Clinically important general adverse effect ‐… compared with sulpiride (very low certainty).

1 finding from 1 review