Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

163 questions · 167 findings · 14 reviews

No studies found 23 · 13.8%GRADE not reported 8 · 4.8%Very low 44 · 26.3%Low 65 · 38.9%Moderate 27 · 16.2%High 0 · 0%

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Misoprostol in abdominal myomectomy · women with uterine fibroids

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in misoprostol in abdominal myomectomy compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Misoprostol in laparoscopic myomectomy · women with uterine fibroids

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in misoprostol in laparoscopic myomectomy compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Balloon (Foley or ATAD) vs low‐dose vaginal misoprostol

Serious neonatal morbidity or perinatal death · third trimester induction of labour in women with a viable fetus

It is very uncertain whether balloon (Foley or ATAD) changes serious neonatal morbidity or perinatal death compared with low‐dose vaginal misoprostol (very low certainty).

1 finding from 1 review

Balloon (Foley or ATAD) vs low‐dose oral misoprostol

Vaginal delivery not achieved within 24 hours · third trimester induction of labour in women with a viable fetus

Balloon (Foley or ATAD) probably leads to higher vaginal delivery not achieved within 24 hours compared with low‐dose oral misoprostol (moderate certainty).

1 finding from 1 review

Balloon (Foley or ATAD) vs low‐dose oral misoprostol

Uterine hyperstimulation with fetal heart rate changes · third trimester induction of labour in women with a viable fetus

Balloon (Foley or ATAD) showed no clear difference in uterine hyperstimulation with FHR changes compared with low‐dose oral misoprostol (low certainty).

1 finding from 1 review

Balloon (Foley or ATAD) vs low‐dose oral misoprostol

Serious neonatal morbidity or perinatal death · third trimester induction of labour in women with a viable fetus

Balloon (Foley or ATAD) showed no clear difference in serious neonatal morbidity or perinatal death compared with low‐dose oral misoprostol (low certainty).

1 finding from 1 review

Balloon (Foley or ATAD) vs low‐dose vaginal misoprostol

Uterine hyperstimulation with fetal heart rate changes · third trimester induction of labour in women with a viable fetus

Balloon (Foley or ATAD) probably leads to lower uterine hyperstimulation with FHR changes compared with low‐dose vaginal misoprostol (moderate certainty).

1 finding from 1 review