Findings

What do systematic reviews say?

146 questions · 215 findings · 13 reviews · Endodontics and dental trauma

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No studies found 3 · 1.4%GRADE not reported 185 · 86%Very low 9 · 4.2%Low 11 · 5.1%Moderate 7 · 3.3%High 0 · 0%

Mineral trioxide aggregate (MTA) pulpotomy dressing vs Triple antibiotic paste (TAP)

Overall success (composite of clinical and radiographic success) · Immature (young) permanent teeth with open apex and vital pulp exposed to dental caries or trauma, in children aged 6-14 years

A single 3-arm RCT found no difference in pulpotomy success between MTA and triple antibiotic paste (both 100%; not pooled; ungraded).

1 finding from 1 review

Materials for pulpotomy in immature permanent teeth: a systematic review and meta-analysis. 2019 All outcomes
1 to 24 months · Pediatric dental clinic (India)
Single RCT (Eppa 2018, 3-arm; 20 MTA and 20 TAP teeth): 100% clinical and radiographic success in both MTA and TAP at all follow-ups (1-24 months); no difference between groups; not pooled
1 study · 40 participants
GRADE not reported

Intervention not reported

Marginal restoration discoloration (adverse event)

1 finding from 1 review

Materials for pulpotomy in immature permanent teeth: a systematic review and meta-analysis. 2019 All outcomes
MTA vs CH (Ozgur 2017)
no estimate extracted
1 study
GRADE not reported

Pulpotomy (full or partial) vs Pulpectomy

Pain · Children with carious vital pulp exposure in primary incisors

No statistically significant difference in pain between pulpotomy and pulpectomy (RR 2.06, 95% CI 0.31 to 13.8; ungraded).

1 finding from 1 review

Pulpotomy versus pulpectomy in the treatment of vital pulp exposure in primary incisors. A systematic review and… 2019 All outcomes
Longest follow-up · Pediatric dental clinics (Canada, USA, Iran; general or local anaesthesia)
RR 2.06 [0.31, 13.8]
Studies not reported
GRADE not reported

Pulpotomy (full or partial) vs Pulpectomy

Pulp canal obliteration · Children with carious vital pulp exposure in primary incisors

Pulp canal obliteration was reported narratively (mainly in the pulpotomy group) and was not pooled.

1 finding from 1 review

Pulpotomy versus pulpectomy in the treatment of vital pulp exposure in primary incisors. A systematic review and… 2019 All outcomes
23-24 months · Pediatric dental clinics (Canada, USA, Iran; general or local anaesthesia)
Pulp canal obliteration seen in 18 teeth (60%) in the pulpotomy group at 23 months (Howley et al.); none at 2 years (Aminabadi et al.); 3 teeth (25%) in the pulpotomy group at 2 years (Casas et al.). Not pooled.
3 studies
GRADE not reported

Intervention not reported

Clinical and radiographic success

1 finding from 1 review

Materials for pulpotomy in immature permanent teeth: a systematic review and meta-analysis. 2019 All outcomes
MTA vs CH, 18 and 24 months (Ozgur 2017)
no estimate extracted
1 study
GRADE not reported

Intervention not reported

Overall failure

1 finding from 1 review

Pulpotomy versus pulpectomy in the treatment of vital pulp exposure in primary incisors. A systematic review and… 2018 All outcomes
no estimate extracted
2 studies
GRADE not reported