Patient preference · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Metronidazole gel (25%, intrasocket) showed no clear difference in presence of dry socket compared with placebo gel; GRADE not reported.
1 finding from 1 review
Restoration failure · Children with carious primary teeth
No comparative effect estimate was reported; the review reports this three-arm comparison but tabulates only compomer failure.
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Metapex (calcium hydroxide/iodoform) showed no clear difference in radiological failure compared with endoflas chlorophenol free (Endoflas-CF); GRADE not reported.
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Metapex (calcium hydroxide/iodoform) showed no clear difference in radiological failure compared with endoflas (CH + ZOE + iodoform); GRADE not reported.
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Metapex (calcium hydroxide/iodoform) showed no clear difference in clinical failure compared with zinc oxide and propolis (ZOP); GRADE not reported.
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Metapex (calcium hydroxide/iodoform) showed no clear difference in clinical failure compared with endoflas chlorophenol free (Endoflas-CF); GRADE not reported.
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Metapex (calcium hydroxide/iodoform) showed no clear difference in clinical failure compared with endoflas (CH + ZOE + iodoform); GRADE not reported.
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Metapex (calcium hydroxide/iodoform) showed no clear difference in clinical failure compared with zinc oxide and eugenol (ZOE) (moderate certainty).
1 finding from 1 review
Metapex (calcium hydroxide/iodoform) vs RC Fill (ZOE with iodoform)
Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
Assessed pain, radiolucency, root resorption, filling material anomaly (Ramar 2010); no significant differences
1 study · 64 participants
GRADE not reported
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Metapex (calcium hydroxide/iodoform) showed no clear difference in radiological failure compared with zinc oxide and eugenol (ZOE) (moderate certainty).
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Metapex (calcium hydroxide/iodoform) showed no clear difference in radiological failure compared with zinc oxide and propolis (ZOP); GRADE not reported.
1 finding from 1 review
Discomfort during treatment · Children (3-10 years) with dentine caries in primary molars
The reported estimate for treatment discomfort with the Hall Technique versus conventional restorations was inconclusive (ungraded).
1 finding from 1 review
RR 1.67 [0.65, 4.25]
2 studies
GRADE not reported
Adverse events: gingival bleeding · Children (3-10 years) with dentine caries in primary molars
The reported estimate for gingival bleeding with preformed metal crowns was inconclusive (ungraded).
1 finding from 1 review
RR 1.09 [0.42, 2.86]
2 studies
GRADE not reported
Restoration failure · Children (3-10 years) with dentine caries in primary molars
The Hall Technique was reported to reduce restoration and major failure versus conventional restorations (3% vs 37%; ungraded).
1 finding from 1 review
3% (HT) vs 37% (control)
1 study
GRADE not reported
Clinical resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment
1 finding from 1 review
Side effects · People with erosive oral lichen planus
1 finding from 1 review
Table 3 (Side-effects). Malhotra 2008: betamethasone oral mini-pulse - transient oedema over the face (7), oedema over hands and feet (4), epigastric discomfort (7), weakness/fatigue (5), loose stools (1), headache…
1 study · 22 participants
GRADE not reported
Investigator‐ or physician‐rated global assessment of disease severity · People with erosive oral lichen planus
Betamethasone oral mini-pulse therapy led to higher physician Global Assessment (clinical severity, 0-12 score) compared with topical triamcinolone acetonide 0.1% paste; GRADE not reported.
1 finding from 1 review
Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
It is very uncertain whether intralesional dexamethasone injections changes maximal mouth opening (interincisal distance) compared with placebo injections (very low certainty).
2 findings from 1 review
Burning sensation (VAS 0-100) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
It is very uncertain whether intralesional dexamethasone injections changes burning sensation (VAS 0-100) compared with placebo injections (very low certainty).
2 findings from 1 review
MD -52.00 [-62.04, -41.96]
1 study · 25 participants
Very low
MD -46.00 [-53.44, -38.56]
1 study · 25 participants
Very low