Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

249 questions · 255 findings · 18 reviews · Headline outcomes only

No studies found 68 · 26.7%GRADE not reported 5 · 2%Very low 102 · 40%Low 44 · 17.3%Moderate 32 · 12.5%High 4 · 1.6%

Laser photocoagulation vs no intervention

Anatomic measures: partial to complete resolution of the macular oedema with stereoscopic fundus photography or biomicroscopy; leakage on fluorescein angiography (IVFA); and, if available, retinal macular thickness with OCT · people with diabetic macular oedema

Laser photocoagulation probably leads to higher anatomic measures: partial to complete resolution of the macular… compared with no intervention (moderate certainty).

1 finding from 1 review

Endovenous laser ablation (EVLA) vs conventional surgery

Recanalisation or persistence of reflux at 6 weeks · people requiring intervention for short saphenous vein varices

Endovenous laser ablation probably leads to lower recanalisation or persistence of reflux at 6 weeks compared with conventional surgery (moderate certainty).

1 finding from 1 review

Endovenous laser ablation (EVLA) vs conventional surgery

Recurrence of reflux at 1 year · people requiring intervention for short saphenous vein varices

Endovenous laser ablation may leads to lower recurrence of reflux at 1 year compared with conventional surgery (low certainty).

1 finding from 1 review

Endovenous laser ablation (EVLA) vs conventional surgery

Recurrence · people requiring intervention for short saphenous vein varices

Endovenous laser ablation showed no clear difference in clinical evidence of recurrence after 1 year compared with conventional surgery (low certainty).

1 finding from 1 review

Endovenous laser ablation (EVLA) vs conventional surgery

Disease‐specific quality of life · people requiring intervention for short saphenous vein varices
2 findings from 1 review

Ultrasound‐guided foam sclerotherapy vs conventional surgery

Disease‐specific quality of life · people requiring intervention for short saphenous vein varices
2 findings from 1 review

Ultrasound‐guided foam sclerotherapy vs conventional surgery

Recanalisation or persistence of reflux at 6 weeks · people requiring intervention for short saphenous vein varices

Ultrasound‐guided foam sclerotherapy showed no clear difference in recanalisation or persistence of reflux at 6 weeks compared with conventional surgery (low certainty).

1 finding from 1 review

Ultrasound‐guided foam sclerotherapy vs conventional surgery

Recurrence of reflux at 1 year · people requiring intervention for short saphenous vein varices

Ultrasound‐guided foam sclerotherapy showed no clear difference in recurrence of reflux at 1 year compared with conventional surgery (low certainty).

1 finding from 1 review