Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

442 questions · 468 findings · 55 reviews

No studies found 96 · 20.5%GRADE not reported 54 · 11.5%Very low 172 · 36.8%Low 87 · 18.6%Moderate 40 · 8.5%High 19 · 4.1%

Intervention not reported

Upper Respiratory Tract Infection number of episodes per number of months · patients with HIV exposure (children)

The intervention showed no clear difference in upper Respiratory Tract Infection number of episodes per number of… (low certainty).

1 finding from 1 review

Intervention not reported

Visits for watery diarrhoea number of visits with diagnosis watery diarrhoea/all visits · patients with HIV infection or exposure

The intervention may leads to lower visits for watery diarrhoea number of visits with diagnosis watery… (low certainty).

1 finding from 1 review

Intervention not reported

Pneumonia number of visits with diagnosis pneumonia/all visits · patients with HIV infection or exposure

The intervention showed no clear difference in pneumonia number of visits with diagnosis pneumonia/all visits (low certainty).

1 finding from 1 review

Intervention not reported

Upper Respiratory Infections number of visits with diagnosis URI/all visits · patients with HIV infection or exposure

The intervention showed no clear difference in upper Respiratory Infections number of visits with diagnosis URI/all… (low certainty).

1 finding from 1 review

Intervention not reported

Mortality, diarrhoea‐specific hospital deaths due to diarrhoea and/or dehydration · patients with HIV infection or exposure

The intervention showed no clear difference in mortality, diarrhoea‐specific hospital deaths due to diarrhoea… (low certainty).

1 finding from 1 review

Intervention not reported

Respiratory infections hospital admission for pneumonia/empyema · patients with HIV infection or exposure

The intervention showed no clear difference in respiratory infections hospital admission for pneumonia/empyema (low certainty).

1 finding from 1 review

Tixagevimab/cilgavimab vs placebo

Infection with SARS‐CoV‐2 within 6 months · SARS‐CoV‐2 uninfected people without defined exposure, or with potential exposure to SARS‐CoV‐2

Tixagevimab/cilgavimab probably leads to lower infection with SARS‐CoV‐2 within 6 months compared with placebo (moderate certainty).

1 finding from 1 review