Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

197 questions · 210 findings · 27 reviews · Pregnancy and Childbirth

No studies found 87 · 41.4%GRADE not reported 2 · 1%Very low 23 · 11%Low 61 · 29%Moderate 34 · 16.2%High 3 · 1.4%

Lanolin vs no intervention

Nipple pain 5‐point verbal descriptor scale · breastfeeding women with sore nipples

Lanolin showed no clear difference in nipple pain 5‐point verbal descriptor scale compared with no intervention (control group) (low certainty).

3 findings from 1 review

Expressed breast milk vs no intervention

Nipple pain 5‐point verbal descriptor scale · breastfeeding women with sore nipples

Expressed breast milk showed no clear difference in nipple pain 5‐point verbal descriptor scale compared with no intervention (control group) (low certainty).

3 findings from 1 review

Probiotics vs placebo

Incidence of mastitis within 6 months postpartum · postpartum breastfeeding women

Probiotics may leads to lower incidence of mastitis within 6 months postpartum compared with placebo (low certainty).

1 finding from 1 review

Antibiotics vs topical treatments

Incidence of mastitis within 6 months postpartum · postpartum breastfeeding women

Antibiotics showed no clear difference in incidence of mastitis within 6 months postpartum ‐ Antibiotics… compared with topical treatments (low certainty).

2 findings from 1 review