Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

178 questions · 182 findings · 14 reviews

No studies found 67 · 36.8%GRADE not reported 36 · 19.8%Very low 38 · 20.9%Low 30 · 16.5%Moderate 11 · 6%High 0 · 0%

Intervention not reported

Pain on walking (NRS) Scale from 0 to 10 · patients with varus medial osteoarthritis of the knee
1 finding from 1 review

Intervention not reported

Physical function (WOMAC) ‐ 12 months Scale from 0 to 100 · patients with varus medial osteoarthritis of the knee
1 finding from 1 review

Intervention not reported

Health‐related quality of life (HRQoL) Scale from 0 to 1.0 · patients with varus medial osteoarthritis of the knee
1 finding from 1 review

Bracing vs observation

Risk of success curves remaining below 50° · adolescents with idiopathic scoliosis

It is very uncertain whether bracing changes risk of success curves remaining below 50° compared with observation (cohort studies) (very low certainty).

1 finding from 1 review

Bracing vs observation

Risk for at least one adverse event per patient · adolescents with idiopathic scoliosis

It is very uncertain whether bracing changes any adverse event number of participants with at least 1 adverse event compared with observation (cohort studies) (very low certainty).

1 finding from 1 review

Bracing vs observation

Pulmonary disorders, disability, back pain, psychological issues, and cosmetic issues subjective or objective · adolescents with idiopathic scoliosis
1 finding from 1 review

Early loading of mini-screw implant vs Delayed loading of mini-screw implant

Success of the anchorage device · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

Early loading of mini-screw implant showed no clear difference in success of the anchorage device compared with delayed loading of mini-screw implant; GRADE not reported.

1 finding from 1 review

Dual mini-screw implant vs Single mini-screw implant

Residual overjet at the end of treatment · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

The review found no eligible studies for this question.

1 finding from 1 review

Surgical anchorage (mini-screw or mid-palatal implant) vs Conventional anchorage (headgear, transpalatal/palatal arch, etc.)

Acceptability · Patients of any age undergoing orthodontic treatment with fixed appliances and requiring anchorage (adolescents to adults up to 48-54 years)
1 finding from 1 review

Surgical anchorage (mini-screw or mid-palatal implant) vs Conventional anchorage (headgear, transpalatal/palatal arch, etc.)

Adverse events · Patients of any age undergoing orthodontic treatment with fixed appliances and requiring anchorage (adolescents to adults up to 48-54 years)

The review found no eligible studies for this question.

1 finding from 1 review

Surgical anchorage (mini-screw or mid-palatal implant) vs Conventional anchorage (headgear, transpalatal/palatal arch, etc.)

Mesiodistal movement of the upper first permanent molar · Patients of any age undergoing orthodontic treatment with fixed appliances and requiring anchorage (adolescents to adults up to 48-54 years)

Surgical anchorage (mini-screw or mid-palatal implant) probably leads to lower mesiodistal movement of the upper first permanent molar compared with conventional anchorage (headgear, transpalatal/palatal arch, etc.) (moderate certainty).

1 finding from 1 review

Surgical anchorage (mini-screw or mid-palatal implant) vs Conventional anchorage (headgear, transpalatal/palatal arch, etc.)

Success or failure of the anchorage device · Patients of any age undergoing orthodontic treatment with fixed appliances and requiring anchorage (adolescents to adults up to 48-54 years)
1 finding from 1 review

Dual mini-screw implant vs Single mini-screw implant

Success of the anchorage device · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

Dual mini-screw implant showed no clear difference in success of the anchorage device compared with single mini-screw implant; GRADE not reported.

1 finding from 1 review

Dual mini-screw implant vs Single mini-screw implant

Duration of space closure · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

Dual mini-screw implant showed no clear difference in duration of space closure compared with single mini-screw implant; GRADE not reported.

1 finding from 1 review

Surgical anchorage (mini-screw or mid-palatal implant) vs Conventional anchorage (headgear, transpalatal/palatal arch, etc.)

Residual overjet at the end of treatment · Patients of any age undergoing orthodontic treatment with fixed appliances and requiring anchorage (adolescents to adults up to 48-54 years)

The review found no eligible studies for this question.

1 finding from 1 review

Surgical anchorage (mini-screw or mid-palatal implant) vs Conventional anchorage (headgear, transpalatal/palatal arch, etc.)

Patient discomfort · Patients of any age undergoing orthodontic treatment with fixed appliances and requiring anchorage (adolescents to adults up to 48-54 years)
1 finding from 1 review

Surgical anchorage (mini-screw or mid-palatal implant) vs Conventional anchorage (headgear, transpalatal/palatal arch, etc.)

Duration of overall treatment · Patients of any age undergoing orthodontic treatment with fixed appliances and requiring anchorage (adolescents to adults up to 48-54 years)

Surgical anchorage (mini-screw or mid-palatal implant) showed no clear difference in duration of overall treatment compared with conventional anchorage (headgear, transpalatal/palatal arch, etc.) (low certainty).

1 finding from 1 review