Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

412 questions · 450 findings · 63 reviews · Headline outcomes only

No studies found 91 · 20.2%GRADE not reported 34 · 7.6%Very low 151 · 33.6%Low 113 · 25.1%Moderate 50 · 11.1%High 11 · 2.4%

Mixed (BEH/EDU/SUP) intervention vs control

N deemed adherent (≥4 hours/night) · adults with obstructive sleep apnoea

It is very uncertain whether mixed (BEH/EDU/SUP) intervention changes 4.3 N deemed adherent (≥ four hours/night) compared with control (very low certainty).

1 finding from 1 review

Group B cognitive behavioural therapy: cognitive behavioural therapy + risperidone vs placebo and cognitive and behavioural therapies

Prodromal symptoms: transition to psychosis Endpoint data (events) · people in the prodromal stage of psychosis

It is very uncertain whether group B cognitive behavioural therapy: cognitive behavioural therapy… changes prodromal symptoms: transition to psychosis Endpoint data (events) compared with cognitive behavioural therapy + placebo (very low certainty).

1 finding from 1 review

Group B cognitive behavioural therapy: cognitive behavioural therapy + risperidone vs placebo and cognitive and behavioural therapies

Adverse effects: specific ‐ doctors' assessment of adverse effects UKU (events) Medium‐term · people in the prodromal stage of psychosis

It is very uncertain whether group B cognitive behavioural therapy: cognitive behavioural therapy… changes adverse effects: specific ‐ doctors' assessment of adverse effects… compared with cognitive behavioural therapy + placebo (very low certainty).

1 finding from 1 review

Group B cognitive behavioural therapy: cognitive behavioural therapy + risperidone vs placebo and cognitive and behavioural therapies

Satisfaction with treatment: leaving the study early Endpoint data (events) · people in the prodromal stage of psychosis

It is very uncertain whether group B cognitive behavioural therapy: cognitive behavioural therapy… changes satisfaction with treatment: leaving the study early Endpoint data… compared with cognitive behavioural therapy + placebo (very low certainty).

1 finding from 1 review