Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

957 questions · 979 findings · 250 reviews

No studies found 159 · 16.2%GRADE not reported 75 · 7.7%Very low 264 · 27%Low 303 · 30.9%Moderate 138 · 14.1%High 40 · 4.1%

Extended‐release methylphenidate vs placebo

ADHD symptoms · adults with ADHD (available evidence for participants aged between 25 to 53 years old)
3 findings from 1 review

Mood stabilisers vs placebo

Self‐harm Measured by: clinicians Timing of outcome assessment: end of treatment · patients with borderline personality disorder

It is very uncertain whether mood stabilisers changes self‐harm Timing of outcome assessment: end of treatment (52 weeks… compared with placebo (very low certainty).

1 finding from 1 review

Antipsychotics vs placebo

Self‐harm Measured by: clinicians Timing of outcome assessment: end of treatment · patients with borderline personality disorder

It is very uncertain whether antipsychotics changes self‐harm Timing of outcome assessment: end of treatment (8 to 24… compared with placebo (very low certainty).

1 finding from 1 review