Antibiotics vs placebo
Antibiotics leads to higher severity or duration of different clinical symptoms: resolution of… compared with placebo (high certainty).
- OR 1.58 [1.13, 2.22]3 studies · 660 participantsHigh
Antibiotics leads to higher severity or duration of different clinical symptoms: resolution of… compared with placebo (high certainty).
Antibiotics leads to higher side effects: total compared with placebo (high certainty).
Antibiotics leads to higher side effects: diarrhoea compared with placebo (high certainty).
Antibiotics leads to lower clinical failure compared with placebo (high certainty).
Antibiotics may leads to lower treatment failure within 4 weeks ‐ current drugs only compared with placebo (low certainty).
Antibiotics showed no clear difference in adverse events ‐ overall (any adverse events not specified) compared with placebo overall (moderate certainty).
Antibiotics showed no clear difference in all‐cause mortality compared with placebo (low certainty).
Antibiotics showed no clear difference in treatment failure within 4 weeks ‐ current drugs only ‐ inpatient compared with placebo (moderate certainty).
Antibiotics probably leads to lower treatment failure within 4 weeks ‐ drugs not currently used ‐ ICU compared with placebo (moderate certainty).
Antibiotics showed no clear difference in all‐cause mortality ‐ inpatients compared with placebo (moderate certainty).
Antibiotics probably leads to lower all‐cause mortality ‐ ICU patients compared with placebo (moderate certainty).
Antibiotics showed no clear difference in adverse events ‐ diarrhoea compared with placebo overall (moderate certainty).
The review found no eligible studies for this question.
Antibiotics showed no clear difference in symptomatic UTI compared with no treatment (low certainty).
Antibiotics showed no clear difference in antimicrobial resistance compared with no treatment (low certainty).
Antibiotics showed no clear difference in all‐cause mortality compared with no treatment (low certainty).
Antibiotics showed no clear difference in graft loss compared with no treatment (low certainty).
Antibiotics showed no clear difference in acute graft rejection compared with no treatment (low certainty).