Quinolone vs aminoglycosides
Suspected ototoxicity · people (of any age) with CSOM
1 finding from 1 review
- no estimate extracted2 studies · 352 participantsVery low
Findings
What do systematic reviews say?
146 questions · 153 findings · 11 reviews · ENT
No studies found 62 · 40.5%GRADE not reported 1 · 0.7%Very low 58 · 37.9%Low 22 · 14.4%Moderate 8 · 5.2%High 2 · 1.3%
Intervention not reported
Resolution of ear discharge‐ measured at 1 to 2 weeks · CSOM, recurrence of CSOM or suppuration following mastoidectomy or tympanoplasty
The intervention may leads to higher resolution of ear discharge‐ measured at 1 to 2 weeks (low certainty).
1 finding from 1 review
- RR 1.47 [1.2, 1.8]2 studies · 150 participantsLow
Intervention not reported
Resolution of ear discharge ‐ measured after 4 weeks · CSOM, recurrence of CSOM or suppuration following mastoidectomy or tympanoplasty
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Roxithromycin vs placebo
Patient response score Scale from: 1 to 6 · chronic rhinosinusitis in adults
1 finding from 1 review
- Systemic antibiotics for chronic rhinosinusitis without nasal polyps in adults 2011 · Cochrane Headline outcomes onlyno estimate extracted1 study · 64 participantsLow
Roxithromycin vs placebo
Mean change from baseline of SNOT‐20 at the end of treatment Scale from: 0 to 5 · chronic rhinosinusitis in adults
1 finding from 1 review
- Systemic antibiotics for chronic rhinosinusitis without nasal polyps in adults 2011 · Cochrane Headline outcomes onlyno estimate extracted1 study · 64 participantsLow
Roxithromycin vs placebo
Mean change from baseline of SNOT‐20 at 3 months post‐treatment Scale from: 0 to 5 · chronic rhinosinusitis in adults
1 finding from 1 review
- Systemic antibiotics for chronic rhinosinusitis without nasal polyps in adults 2011 · Cochrane Headline outcomes onlyno estimate extracted1 study · 64 participantsLow