Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

291 questions · 293 findings · 75 reviews

No studies found 56 · 19.1%GRADE not reported 24 · 8.2%Very low 61 · 20.8%Low 62 · 21.2%Moderate 39 · 13.3%High 51 · 17.4%

Intervention not reported

Estimation (95% Cl) · children with close tuberculosis contacts Index test: abnormal chest radiography Role: an initial test Threshold for index tests: author…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Pooled sensitivity 87% (75% to 93%) · children with close tuberculosis contacts Index test: abnormal chest radiography Role: an initial test Threshold for index tests: author…
1 finding from 1 review

Intervention not reported

Pooled specificity 99% (68% to 100%) · children with close tuberculosis contacts Index test: abnormal chest radiography Role: an initial test Threshold for index tests: author…
1 finding from 1 review

Long‐term red cell transfusion vs usual care

SCD‐related SAEs ‐ pain crisis · prevention of SCI in people with SCD and abnormal TCD velocities

It is very uncertain whether long‐term RBC transfusion changes SCD‐related SAEs ‐ pain crisis compared with standard care (very low certainty).

1 finding from 1 review