Health‐related quality of life Mean AcroQoL score (0‐100) · adults with growth‐hormone secreting pituitary adenomas
Surgery alone showed no clear difference in health‐related quality of life Mean AcroQoL score (0‐100) compared with pharmacological therapy alone (low certainty).
1 finding from 1 review
Disease‐related complications Intubation difficulties requiring postponement of surgery · adults with growth‐hormone secreting pituitary adenomas
It is very uncertain whether surgery alone changes disease‐related complications Intubation difficulties requiring… compared with preoperative pharmacological therapy and surgery (very low certainty).
1 finding from 1 review
Recurrence · adults with growth‐hormone secreting pituitary adenomas
1 finding from 1 review
Time to complete healing · pilonidal sinus
1 finding from 1 review
Recurrence · pilonidal sinus
It is very uncertain whether summary of findings table ‐ Off‐midline closure changes recurrence rate compared with tension‐free midline closure (very low certainty).
1 finding from 1 review
Wound infection · pilonidal sinus
It is very uncertain whether summary of findings table ‐ Off‐midline closure changes wound infection compared with tension‐free midline closure (very low certainty).
1 finding from 1 review
Wound dehiscence · pilonidal sinus
It is very uncertain whether summary of findings table ‐ Off‐midline closure changes wound dehiscence compared with tension‐free midline closure (very low certainty).
1 finding from 1 review
Return to work · pilonidal sinus
1 finding from 1 review
Quality of life ‐ not reported · pilonidal sinus
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Time to complete healing · pilonidal sinus
1 finding from 1 review
Proportion of wounds healed · pilonidal sinus
Summary of findings table ‐ Off‐midline closure (Karydakis flap) showed no clear difference in proportion of wounds healed compared with off‐midline closure (Limberg flap) (low certainty).
1 finding from 1 review
Recurrence · pilonidal sinus
Summary of findings table ‐ Off‐midline closure (Karydakis flap) showed no clear difference in recurrence rate compared with off‐midline closure (Limberg flap) (low certainty).
1 finding from 1 review
Wound infection · pilonidal sinus
Summary of findings table ‐ Off‐midline closure (Karydakis flap) showed no clear difference in wound infection compared with off‐midline closure (Limberg flap) (low certainty).
1 finding from 1 review
Wound dehiscence · pilonidal sinus
Summary of findings table ‐ Off‐midline closure (Karydakis flap) showed no clear difference in wound dehiscence compared with off‐midline closure (Limberg flap) (low certainty).
1 finding from 1 review
Proportion of wounds healed · pilonidal sinus
It is very uncertain whether summary of findings table ‐ Off‐midline closure changes proportion of wounds healed compared with conventional midline closure (very low certainty).
1 finding from 1 review
Return to work · pilonidal sinus
1 finding from 1 review
Quality of life ‐ not reported · pilonidal sinus
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Recurrence · pilonidal sinus
Summary of findings table ‐ Off‐midline closure probably leads to lower recurrence rate compared with conventional midline closure (moderate certainty).
1 finding from 1 review
Wound infection · pilonidal sinus
Summary of findings table ‐ Off‐midline closure probably leads to lower wound infection compared with conventional midline closure (moderate certainty).
1 finding from 1 review
Wound dehiscence · pilonidal sinus
Summary of findings table ‐ Off‐midline closure may leads to lower wound dehiscence compared with conventional midline closure (low certainty).
1 finding from 1 review