Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,890 questions · 3,917 findings · 272 reviews · Oral Health

No studies found 429 · 11%GRADE not reported 2,657 · 67.8%Very low 512 · 13.1%Low 219 · 5.6%Moderate 80 · 2%High 20 · 0.5%

Prison-nursery setting / incarcerated-mother household (oral health status) vs Counterparts (community children)

Oral health status (caries, oral hygiene, treatment indices) · Preschool children of incarcerated mothers in UAE prison nurseries

One study found high caries (89.8%) and poor oral hygiene with low restorative care among preschool children of incarcerated mothers (narrative synthesis; not GRADE-rated).

1 finding from 1 review

Coaxial nickel-titanium archwire vs Nickel-titanium archwire

Amount of tooth movement / reduction in crowding at 12 weeks · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

It is very uncertain whether coaxial nickel-titanium archwire changes amount of tooth movement / reduction in crowding at 12 weeks compared with nickel-titanium archwire (very low certainty).

1 finding from 1 review

Other visual classification systems (unspecified or unique systems, e.g. Nyvad, Downer, Lussi, UniViSS) vs Reference standard (histology, excavation, radiographs/microCT, or tooth separation)

Specificity for detection of enamel caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
1 finding from 1 review

Gingivitis (assessed by gingival index or WHO criteria) vs None (descriptive prevalence review; subgroup analyses by urban/rural status, country and year)

Gingival health at 6 months · Children and adolescents in the United Arab Emirates (Sharjah)

Gingivitis and high plaque levels were common among UAE children and adolescents, more likely in females and older children (narrative synthesis; not GRADE-rated).

1 finding from 1 review

Vibrational appliance with fixed appliances vs Fixed appliances

Time to alignment · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

Vibrational appliance with fixed appliances showed no clear difference in time to alignment (days) compared with fixed appliances only / no vibrational appliance (control); GRADE not reported.

1 finding from 1 review

Digital radiographs vs Reference standard (histology, excavation, or enhanced visual examination)

Sensitivity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
1 finding from 1 review

Radiographic imaging methods (any: analogue radiographs, digital radiographs, or CBCT) vs Reference standard (histology, excavation, or enhanced visual examination)

Diagnostic accuracy on surfaces with pit and fissure sealants · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…

The review found no eligible studies for this question.

1 finding from 1 review
  • Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomes
    Up to 3 months between index test and reference standard (in vivo studies) · Pit and fissure sealants
    Pre-specified heterogeneity investigation of surfaces with pit and fissure sealants: no study reported the inclusion of sealants that would allow evaluation of early caries lesions.
    0 studies
    No studies found

Self-ligating brackets vs Conventional brackets

Amount of crowding (lower incisor crowding) at 10 weeks · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

It is very uncertain whether self-ligating brackets changes amount of crowding (lower incisor crowding) at 10 weeks compared with conventional brackets (very low certainty).

1 finding from 1 review

Near-infrared (NIR) transillumination vs Reference standard (histology, excavation, radiographs/microCT, or tooth separation)

Specificity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
1 finding from 1 review

Digital radiographs vs Reference standard (histology, excavation, or enhanced visual examination)

Specificity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
1 finding from 1 review

Restorative dental treatment under general anesthesia vs Before treatment (before-after)

Oral health-related quality of life (child and family) · Preschool children in the United Arab Emirates receiving dental general anesthesia

One study found restorative dental treatment under general anesthesia significantly improved oral health-related quality of life for preschool children and their families (narrative synthesis; not GRADE-rated).

1 finding from 1 review

Visual classification: ERK (Ekstrand-Ricketts-Kidd system) vs Reference standard (histology, excavation, radiographs/microCT, or tooth separation)

Specificity for detection of enamel caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
1 finding from 1 review

Extraction of lower deciduous canines vs No active treatment (control)

Amount of crowding · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

It is very uncertain whether extraction of lower deciduous canines changes amount of crowding (lower incisor crowding, change) at 1-2 years compared with no active treatment (control) (very low certainty).

1 finding from 1 review

Early childhood caries (ECC) vs Caries-free controls

Iron deficiency (as defined by trialists) · Preschool children (<6 years)

In a sensitivity analysis excluding one outlier study, ECC remained associated with higher odds of iron deficiency (OR 2.76, 95% CI 2.42 to 3.13); ungraded.

2 findings from 1 review

Optical coherence tomography (OCT) vs Reference standard (histology, excavation, radiographs/microCT, or tooth separation)

Sensitivity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
1 finding from 1 review

Visual or visual-tactile classification systems (any system: ICDAS, ERK, Nyvad, Downer, Lussi, UniViSS, or unspecified) vs Reference standard (histology, excavation, radiographs/microCT, or tooth separation)

Diagnostic accuracy on surfaces with pit and fissure sealants · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…

The review found no eligible studies for this question.

1 finding from 1 review

Lower lip bumper vs No active treatment (control)

Lower molars to mandible (relationship of lower back teeth to the mandible) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

Lower lip bumper led to lower lower molars to mandible at 6 months compared with no active treatment (control); GRADE not reported.

1 finding from 1 review