Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,760 questions · 8,065 findings · 1,036 reviews

No studies found 1,686 · 20.9%GRADE not reported 675 · 8.4%Very low 1,953 · 24.2%Low 2,048 · 25.4%Moderate 1,296 · 16.1%High 407 · 5%

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Summary of findings: IMRT vs 3DCRT

Mean GI symptom scores (EORTC‐QLQPR25 scale; lower scores better) · People with urological (prostate) and gynaecological (cervical) cancer

Summary of findings: IMRT showed no clear difference in mean GI symptom scores (EORTC‐QLQPR25 scale; lower scores better) compared with 3DCRT (low certainty).

1 finding from 1 review

Summary of findings: lipid‐based nutrient supplements (LNS) vs multiple micronutrients (MMN)

Low birth weight (< 2.5 kg) · pregnant women

Summary of findings: lipid‐based nutrient supplements (LNS) showed no clear difference in low birth weight (< 2500 g) compared with multiple micronutrients (MMN) (moderate certainty).

1 finding from 1 review

Summary of findings: lipid‐based nutrient supplements (LNS) vs iron folic acid (IFA)

Low birth weight (< 2.5 kg) · pregnant women

Summary of findings: lipid‐based nutrient supplements (LNS) showed no clear difference in low birth weight (< 2500 g) compared with iron folic acid (IFA) (moderate certainty).

1 finding from 1 review

LABA/LAMA vs LAMA

Severe exacerbations: low‐risk population · chronic obstructive pulmonary disease with predicted FEV1 of less than 80%

LABA/LAMA showed no clear difference in severe exacerbations: low‐risk population compared with LAMA (moderate certainty).

1 finding from 1 review

LABA/LAMA vs LABA

Moderate to severe exacerbations: low‐risk population · chronic obstructive pulmonary disease with predicted FEV1 of less than 80%

LABA/LAMA probably leads to lower moderate to severe exacerbations: low‐risk population compared with LABA (moderate certainty).

1 finding from 1 review

LABA/LAMA vs LABA

Severe exacerbations: low‐risk population · chronic obstructive pulmonary disease with predicted FEV1 of less than 80%

LABA/LAMA showed no clear difference in severe exacerbations: low‐risk population compared with LABA (moderate certainty).

1 finding from 1 review

LABA/LAMA vs LABA plus inhaled corticosteroid (ICS)

Moderate to severe exacerbations: low‐risk population · chronic obstructive pulmonary disease with predicted FEV1 of less than 80%

LABA/LAMA showed no clear difference in moderate to severe exacerbations: low‐risk population compared with LABA/ICS (moderate certainty).

1 finding from 1 review

LABA/ICS vs LAMA

Moderate to severe exacerbations: low‐risk population · chronic obstructive pulmonary disease with predicted FEV1 of less than 80%

LABA/ICS showed no clear difference in moderate to severe exacerbations: low‐risk population compared with LAMA (low certainty).

1 finding from 1 review

LABA/ICS vs LABA

Moderate to severe exacerbations: low‐risk population · chronic obstructive pulmonary disease with predicted FEV1 of less than 80%

LABA/ICS probably leads to lower moderate to severe exacerbations: low‐risk population compared with LABA (moderate certainty).

1 finding from 1 review

LAMA vs LABA

Moderate to severe exacerbations: low‐risk population · chronic obstructive pulmonary disease with predicted FEV1 of less than 80%

LAMA showed no clear difference in moderate to severe exacerbations: low‐risk population compared with LABA (moderate certainty).

1 finding from 1 review