Findings

What do systematic reviews say?

2,359 questions · 2,491 findings · 249 reviews

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No studies found 696 · 27.9%GRADE not reported 213 · 8.6%Very low 611 · 24.5%Low 595 · 23.9%Moderate 315 · 12.6%High 61 · 2.4%

Medium‐dose UVA‐1 phototherapy (50 J/cm²) vs low‐dose UVA‐1 phototherapy (20 J/cm²)

Secondary outcome: Improvement of disease activity (skin softening) · children and adults with active morphea (circumscribed morphea, linear scleroderma (with trunk/limb variant and head variant), generalised…

1 finding from 1 review

Interventions for morphea 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 36 participants
Low

Medium‐dose UVA‐1 phototherapy (50 J/cm²) vs low‐dose UVA‐1 phototherapy (20 J/cm²)

Secondary outcome: Improvement of disease damage ‐ not measured · children and adults with active morphea (circumscribed morphea, linear scleroderma (with trunk/limb variant and head variant), generalised…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for morphea 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

NB‐UVB vs medium‐dose UVA‐1 phototherapy (50 J/cm²)

Primary outcome: Global improvement of disease activity or damage assessed by a medical practitioner or by participants · children and adults with active morphea (circumscribed morphea, linear scleroderma (with trunk/limb variant and head variant), generalised…

1 finding from 1 review

Interventions for morphea 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 35 participants
Low

Conventional occlusion vs atropine penalization

Visual acuity · Participants of any age with either unilateral strabismic, anisometropic, or mixed (strabismic‐refractive) amblyopia; deprivation…

2 findings from 1 review

Conventional occlusion versus pharmacologic penalization for amblyopia 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 552 participants
Moderate
Conventional occlusion versus pharmacologic penalization for amblyopia 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 483 participants
Moderate

Conventional occlusion vs atropine penalization

Adherence · Participants of any age with either unilateral strabismic, anisometropic, or mixed (strabismic‐refractive) amblyopia; deprivation…

1 finding from 1 review

Conventional occlusion versus pharmacologic penalization for amblyopia 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 588 participants
Moderate

Conventional occlusion vs atropine penalization

Ocular alignment (different measures and time points reported in the included studies) Assessed at different time points (17 weeks, 24 months, or cessation of treatment) and by the proportions of participants who developed strabismus, showed chang... · Participants of any age with either unilateral strabismic, anisometropic, or mixed (strabismic‐refractive) amblyopia; deprivation…

1 finding from 1 review

Conventional occlusion versus pharmacologic penalization for amblyopia 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 888 participants
Moderate

Conventional occlusion vs atropine penalization

Stereo acuity (different measures and time points reported in the included studies) Assessed at different time points (17 weeks, 6 months, 2 years, or at cessation of treatment) and using different measures (TNO stereo test, Titmus fly test, Rando... · Participants of any age with either unilateral strabismic, anisometropic, or mixed (strabismic‐refractive) amblyopia; deprivation…

1 finding from 1 review

Conventional occlusion versus pharmacologic penalization for amblyopia 2019 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 865 participants
Moderate

Conventional occlusion vs atropine penalization

Quality of life (different measures and time points reported in the included studies) Assessed at different time points (17 weeks or 6 months) by patient preference or the Amblyopia Treatment Index questionnaire. · Participants of any age with either unilateral strabismic, anisometropic, or mixed (strabismic‐refractive) amblyopia; deprivation…

1 finding from 1 review

Conventional occlusion versus pharmacologic penalization for amblyopia 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 256 participants
Moderate

Conventional occlusion vs atropine penalization

Adverse events (reported occurrence of: mild reduction in the visual acuity of the sound eye not requiring treatment; light sensitivity; skin, lid, or conjunctival irritation) Assessed at different time points (17 weeks or 2 years). · Participants of any age with either unilateral strabismic, anisometropic, or mixed (strabismic‐refractive) amblyopia; deprivation…

1 finding from 1 review

Conventional occlusion versus pharmacologic penalization for amblyopia 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 612 participants
High

Any early psychological intervention vs active control

Depressive symptoms · various

1 finding from 1 review

Multiple session early psychological interventions for the prevention of post‐traumatic stress disorder 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 409 participants
Low

Any early psychological intervention vs active control

Anxiety · various

1 finding from 1 review

Multiple session early psychological interventions for the prevention of post‐traumatic stress disorder 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 414 participants
Low

Any early psychological intervention vs active control

General functioning ‐ not measured · various

1 finding from 1 review

Multiple session early psychological interventions for the prevention of post‐traumatic stress disorder 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 239 participants
Low

Any early psychological intervention vs active control

Dropout · various

Any early psychological intervention may leads to higher dropouts from treatment compared with active control condition (low certainty).

1 finding from 1 review

Multiple session early psychological interventions for the prevention of post‐traumatic stress disorder 2019 · Cochrane Headline outcomes only
RR 1.61 [1.11, 2.34]
2 studies · 425 participants
Low

Any early psychological intervention vs active control

Severity of PTSD symptoms · various

1 finding from 1 review

Multiple session early psychological interventions for the prevention of post‐traumatic stress disorder 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 465 participants
Low

Summary of findings: Specialist inpatient care for weight restoration vs active outpatient or combination brief hospital/outpatient care

Weight or BMI (at end of 12 months from the start of treatment) · participants with anorexia nervosa

Summary of findings: Specialist inpatient care for weight restoration showed no clear difference in weight or BMI (at end of 12 months from the start of treatment) compared with active outpatient or combination brief hospital/outpatient care (low certainty).

1 finding from 1 review

Inpatient versus outpatient care, partial hospitalisation and waiting list for people with eating disorders 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 232 participants
Low

Summary of findings: Specialist inpatient care for weight restoration vs active outpatient or combination brief hospital/outpatient care

Secondary outcome: acceptability of treatment · participants with anorexia nervosa

It is very uncertain whether summary of findings: Specialist inpatient care for weight restoration changes acceptability: number of participants who completed treatment (at… compared with active outpatient or combination brief hospital/outpatient care (very low certainty).

1 finding from 1 review

Inpatient versus outpatient care, partial hospitalisation and waiting list for people with eating disorders 2019 · Cochrane Headline outcomes only
RR 0.75 [0.64, 0.88]
3 studies · 319 participants
Very low

Positional therapy vs inactive control

Adherence · adults with obstructive sleep apnoea

1 finding from 1 review

Positional therapy for obstructive sleep apnoea 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 101 participants
Low

Positional therapy vs inactive control

Adverse effects Measured as number of participants who discontinued device at end of 2 months · adults with obstructive sleep apnoea

1 finding from 1 review

Positional therapy for obstructive sleep apnoea 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 101 participants
Low

Positional therapy vs inactive control

Quality of life Assessed using SF‐36 or FOSQ · adults with obstructive sleep apnoea

1 finding from 1 review

Positional therapy for obstructive sleep apnoea 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 86 participants
Moderate

Positional therapy vs inactive control

Sleep quality Assessed by average duration of slow‐wave and REM sleep periods · adults with obstructive sleep apnoea

1 finding from 1 review

Positional therapy for obstructive sleep apnoea 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Low