Findings

What do systematic reviews say?

2,447 questions · 2,590 findings · 266 reviews

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No studies found 699 · 27%GRADE not reported 289 · 11.2%Very low 614 · 23.7%Low 605 · 23.4%Moderate 322 · 12.4%High 61 · 2.4%

Probiotics vs 5‐aminosalicylic acid (5‐ASA) (mesalazine)

Serious adverse events · people with active UC

It is very uncertain whether probiotics changes serious adverse events compared with 5‐aminosalicylic acid (5‐ASA) (mesalazine) (very low certainty).

1 finding from 1 review

Probiotics for induction of remission in ulcerative colitis 2020 · Cochrane Headline outcomes only
RR 0.21 [0.01, 4.22]
1 study · 116 participants
Very low

Probiotics vs 5‐aminosalicylic acid (5‐ASA) (mesalazine)

Withdrawals due to adverse events · people with active UC

It is very uncertain whether probiotics changes withdrawal due to adverse events compared with 5‐aminosalicylic acid (5‐ASA) (mesalazine) (very low certainty).

1 finding from 1 review

Probiotics for induction of remission in ulcerative colitis 2020 · Cochrane Headline outcomes only
RR 0.21 [0.01, 4.22]
1 study · 116 participants
Very low

Psychological therapies and/or group programmes vs active control

Health‐related quality of life · adults (>= 18 years) with an irreversible visual impairment

1 finding from 1 review

Low vision rehabilitation for better quality of life in visually impaired adults 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 600 participants
Very low

Psychological therapies and/or group programmes vs active control

Vision‐related quality of life · adults (>= 18 years) with an irreversible visual impairment

1 finding from 1 review

Low vision rehabilitation for better quality of life in visually impaired adults 2020 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 1245 participants
Low

Psychological therapies and/or group programmes vs active control

Adverse events · adults (>= 18 years) with an irreversible visual impairment

1 finding from 1 review

Low vision rehabilitation for better quality of life in visually impaired adults 2020 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 1453 participants
Very low

Methods of enhancing vision and/or group programmes vs active control

Health‐related quality of life · adults (>= 18 years) with an irreversible visual impairment

1 finding from 1 review

Low vision rehabilitation for better quality of life in visually impaired adults 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 443 participants
Very low

Methods of enhancing vision and/or group programmes vs active control

Vision‐related quality of life · adults (>= 18 years) with an irreversible visual impairment

1 finding from 1 review

Low vision rehabilitation for better quality of life in visually impaired adults 2020 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 660 participants
Moderate

Methods of enhancing vision and/or group programmes vs active control

Adverse events · adults (>= 18 years) with an irreversible visual impairment

1 finding from 1 review

Low vision rehabilitation for better quality of life in visually impaired adults 2020 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 660 participants
Very low

Multidisciplinary rehabilitation vs active control

Health‐related quality of life · adults (>= 18 years) with an irreversible visual impairment

1 finding from 1 review

Low vision rehabilitation for better quality of life in visually impaired adults 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 375 participants
Very low

Multidisciplinary rehabilitation vs active control

Vision‐related quality of life · adults (>= 18 years) with an irreversible visual impairment

1 finding from 1 review

Low vision rehabilitation for better quality of life in visually impaired adults 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 464 participants
Low

Multidisciplinary rehabilitation vs active control

Adverse events · adults (>= 18 years) with an irreversible visual impairment

1 finding from 1 review

Low vision rehabilitation for better quality of life in visually impaired adults 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 464 participants
GRADE not reported

Radical prostatectomy vs active monitoring

Time to disease progressionMedian · clinically localized prostate cancer

Radical prostatectomy probably leads to lower time to disease progressionMedian compared with active monitoring (moderate certainty).

1 finding from 1 review

Radical prostatectomy versus deferred treatment for localised prostate cancer 2020 · Cochrane Headline outcomes only
HR 0.39 [0.27, 0.56]
1 study · 1098 participants
Moderate

Radical prostatectomy vs active monitoring

Incidence of metastatic diseaseMedian · clinically localized prostate cancer

Radical prostatectomy probably leads to lower incidence of metastatic diseaseMedian compared with active monitoring (moderate certainty).

1 finding from 1 review

Radical prostatectomy versus deferred treatment for localised prostate cancer 2020 · Cochrane Headline outcomes only
RR 0.39 [0.21, 0.73]
1 study · 1098 participants
Moderate

Radical prostatectomy vs active monitoring

Health‐related quality of life · clinically localized prostate cancer

1 finding from 1 review

Radical prostatectomy versus deferred treatment for localised prostate cancer 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 856 participants
Moderate

Radical prostatectomy vs active monitoring

Urinary function · clinically localized prostate cancer

1 finding from 1 review

Radical prostatectomy versus deferred treatment for localised prostate cancer 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 782 participants
Low

Radical prostatectomy vs active monitoring

Effect on later sexual function · clinically localized prostate cancer

1 finding from 1 review

Radical prostatectomy versus deferred treatment for localised prostate cancer 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 756 participants
Low

Radical prostatectomy vs active monitoring

Time to death from any causeMedian · clinically localized prostate cancer

Radical prostatectomy showed no clear difference in time to death from any causeMedian compared with active monitoring (moderate certainty).

1 finding from 1 review

Radical prostatectomy versus deferred treatment for localised prostate cancer 2020 · Cochrane Headline outcomes only
HR 0.93 [0.65, 1.33]
1 study · 1098 participants
Moderate

Radical prostatectomy vs active monitoring

Time to death from prostate cancerMedian · clinically localized prostate cancer

Radical prostatectomy showed no clear difference in time to death from prostate cancerMedian compared with active monitoring (moderate certainty).

1 finding from 1 review

Radical prostatectomy versus deferred treatment for localised prostate cancer 2020 · Cochrane Headline outcomes only
HR 0.63 [0.21, 1.89]
1 study · 1098 participants
Moderate

Low molecular weight heparin vs active control

Symptomatic VTE · ambulatory cancer patients receiving chemotherapy

Low‐molecular‐weight heparin showed no clear difference in symptomatic VTE compared with with active control (1) (low certainty).

3 findings from 1 review

Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy 2020 · Cochrane Headline outcomes only
RR 2.89 [0.12, 66.75]
1 study · 51 participants
Low
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy 2020 · Cochrane Headline outcomes only
RR 0.51 [0.22, 1.17]
2 studies · 781 participants
Moderate
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy 2020 · Cochrane Headline outcomes only
RR 0.33 [0.14, 0.83]
1 study · 439 participants
High

Low molecular weight heparin vs active control

Major bleeding · ambulatory cancer patients receiving chemotherapy

The review found no eligible studies for this question.

3 findings from 1 review

Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy 2020 · Cochrane Headline outcomes only
RR 0.14 [0.01, 2.76]
2 studies · 781 participants
Low
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found