Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,434 questions · 2,594 findings · 269 reviews

No studies found 543 · 20.9%GRADE not reported 191 · 7.4%Very low 676 · 26.1%Low 732 · 28.2%Moderate 399 · 15.4%High 53 · 2%

Additional support vs usual care

Death of a baby (stillbirth or neonatal death) report of perinatal death · women at increased risk of low birthweight babies (maternal outcomes)

Additional support showed no clear difference in stillbirth/neonatal death compared with usual care during pregnancy (low certainty).

1 finding from 1 review

Additional support vs usual care

Number of antenatal hospital admissions · women at increased risk of low birthweight babies (maternal outcomes)

Additional support probably leads to lower antenatal hospital admissions Number of admissions per woman compared with usual care during pregnancy (moderate certainty).

2 findings from 1 review

Additional support vs usual care

Postnatal depression · women at increased risk of low birthweight babies (maternal outcomes)

Additional support showed no clear difference in postnatal depression Self‐reported compared with usual care during pregnancy (low certainty).

2 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Instrumented gait analysis (kinematics) (not measured) · children with CP

The review found no eligible studies for this question.

3 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Function · children with CP
3 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Range of motion (passive ankle dorsiflexion) · children with CP
3 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Satisfaction (not measured) · children with CP

The review found no eligible studies for this question.

2 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Spasticity (ankle plantarflexors) · children with CP
3 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Adverse events · children with CP

The review found no eligible studies for this question.

3 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Gait assessment ‐ not measured · children with CP

The review found no eligible studies for this question.

2 findings from 1 review