Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,720 questions · 15,377 findings · 900 reviews

No studies found 3,865 · 25.1%GRADE not reported 2,291 · 14.9%Very low 3,875 · 25.2%Low 3,287 · 21.4%Moderate 1,681 · 10.9%High 378 · 2.5%

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Familiar odour (breast milk smell) vs usual care

Pain (PIPP) · neonates with mechanical ventilation

Familiar odour (breast milk smell) showed no clear difference in PIPP during endotracheal suctioning Range of scale 0 to 21. Lower… compared with standard care (low certainty).

1 finding from 1 review

Facilitated tucking / four‐handed care / gentle human touch vs usual care

Pain (PIPP) · neonates with mechanical ventilation

Facilitated tucking / four‐handed care / gentle human touch showed no clear difference in PIPP during endotracheal suctioning Range of scale 0 to 21. Lower… compared with standard care (moderate certainty).

1 finding from 1 review

Facilitated tucking / four‐handed care / gentle human touch vs usual care

Heart rate · neonates with mechanical ventilation

Facilitated tucking / four‐handed care / gentle human touch showed no clear difference in heart rate compared with standard care (low certainty).

1 finding from 1 review

Facilitated tucking / four‐handed care / gentle human touch vs usual care

SaO 2 during endotracheal suctioning · neonates with mechanical ventilation

Facilitated tucking / four‐handed care / gentle human touch showed no clear difference in saO 2 during endotracheal suctioning compared with standard care (low certainty).

1 finding from 1 review

Facilitated tucking / four‐handed care / gentle human touch vs usual care

SDB during endotracheal suctioning · neonates with mechanical ventilation

Facilitated tucking / four‐handed care / gentle human touch showed no clear difference in SDB during endotracheal suctioning compared with standard care (low certainty).

1 finding from 1 review

Facilitated tucking / four‐handed care / gentle human touch vs usual care

SRB during endotracheal suctioning · neonates with mechanical ventilation

Facilitated tucking / four‐handed care / gentle human touch may leads to higher SRB during endotracheal suctioning compared with standard care (low certainty).

1 finding from 1 review