Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

1,835 questions · 1,886 findings · 74 reviews · Skin

No studies found 542 · 28.7%GRADE not reported 130 · 6.9%Very low 326 · 17.3%Low 434 · 23%Moderate 348 · 18.5%High 106 · 5.6%

Ciclopirox vs placebo

Side effects (combined for face and scalp) Self report · patients with seborrhoeic dermatitis

Ciclopirox showed no clear difference in side effects (combined for face and scalp) Self reported compared with placebo (moderate certainty).

1 finding from 1 review

Ketoconazole vs placebo

Side effects Self report · patients with seborrhoeic dermatitis

It is very uncertain whether ketoconazole changes side effects Self report compared with placebo (very low certainty).

1 finding from 1 review

Ketoconazole vs steroids

Failure to achieve complete resolution (combined for face and scalp) Clinical assessment · patients with seborrhoeic dermatitis

Ketoconazole showed no clear difference in failure to achieve complete resolution (combined for face and scalp)… compared with steroids (low certainty).

1 finding from 1 review

Ketoconazole vs steroids

Side effects (combined for face and scalp) Self report · patients with seborrhoeic dermatitis

Ketoconazole probably leads to lower side effects (combined for face and scalp) Self report compared with steroids (moderate certainty).

1 finding from 1 review

Ketoconazole vs ciclopirox

Failure to achieve complete resolution ‐ Face only Clinical assessment · patients with seborrhoeic dermatitis

Ketoconazole showed no clear difference in failure to achieve complete resolution ‐ Face only Clinical assessment compared with ciclopirox (low certainty).

1 finding from 1 review

Ketoconazole vs ciclopirox

Failure to achieve complete resolution (long term) ‐ Face only Clinical assessment · patients with seborrhoeic dermatitis

Ketoconazole showed no clear difference in failure to achieve complete resolution (long term) ‐ Face only… compared with ciclopirox (low certainty).

1 finding from 1 review

Ketoconazole vs ciclopirox

Side effects ‐ Scalp only Self reported · patients with seborrhoeic dermatitis

It is very uncertain whether ketoconazole changes side effects ‐ Scalp only Self reported compared with ciclopirox (very low certainty).

1 finding from 1 review

Ciclopirox vs placebo

Failure to achieve complete resolution (combined for face and scalp) Clinical assessment · patients with seborrhoeic dermatitis

Ciclopirox probably leads to lower failure to achieve complete resolution (combined for face and scalp)… compared with placebo (moderate certainty).

1 finding from 1 review

Intervention not reported

Clinician‐assessed global eczema severity using a named scale (Leicester Sign Score) · children and adults with eczema with proven sensitivity to house dust mite
1 finding from 1 review

Intervention not reported

Clinician‐assessed global eczema severity using a named scale (SASSAD) · children and adults with eczema with proven sensitivity to house dust mite
1 finding from 1 review

Intervention not reported

Clinician‐assessed global eczema severity using a named scale (SCORAD) · children and adults with eczema with proven sensitivity to house dust mite
1 finding from 1 review

Intervention not reported

Participant‐ or caregiver‐assessed eczema‐related quality of life (named instrument) · children and adults with eczema with proven sensitivity to house dust mite
1 finding from 1 review

Herbal medicines vs antibiotics alone

Remission · participants with acne

Herbal medicine showed no clear difference in secondary outcome: number of participants with remission (ITT‐best… compared with antibiotics (low certainty).

2 findings from 1 review

Tacrolimus 0.1% vs corticosteroids

Physician's assessment of global response of improvement, clear or excellent ‐ 6 weeks · people with atopic dermatitis

Tacrolimus 0.1% probably leads to higher physician's assessment of global response of improvement, clear or… compared with corticosteroids (moderate certainty).

3 findings from 1 review

Tacrolimus 0.03% vs corticosteroids

Physician's assessment of global response of improvement, clear or excellent ‐ 6 weeks · people with atopic dermatitis

Tacrolimus 0.03% probably leads to higher physician's assessment of global response of improvement, clear or… compared with corticosteroids (moderate certainty).

4 findings from 1 review
Show 1 more finding

Tacrolimus 0.03% vs corticosteroids

Participant's self‐assessment of global response of improvement: tacrolimus 0.03% 2x/day versus hydrocortisone acetate 1% 2x/day · people with atopic dermatitis

Tacrolimus 0.03% probably leads to higher participant's self‐assessment of global response of improvement:… compared with corticosteroids (moderate certainty).

1 finding from 1 review

Tacrolimus 0.03% vs Topical tacrolimus

Physician's assessment of global response of improvement · people with atopic dermatitis

Tacrolimus 0.03% leads to lower physician's assessment of global response of improvement, clear or… compared with tacrolimus 0.1% (high certainty).

1 finding from 1 review