Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,288 questions · 3,354 findings · 516 reviews · Headline outcomes only

No studies found 720 · 21.5%GRADE not reported 164 · 4.9%Very low 950 · 28.3%Low 932 · 27.8%Moderate 434 · 12.9%High 154 · 4.6%

Pre‐emptive antifungal therapy vs empirical antifungal therapy

All‐cause mortality · people with cancer who have febrile neutropenia

Pre‐emptive antifungal therapy showed no clear difference in all‐cause mortality compared with empirical antifungal therapy (low certainty).

1 finding from 1 review

Pre‐emptive antifungal therapy vs empirical antifungal therapy

Mortality ascribed to fungal infection · people with cancer who have febrile neutropenia

Pre‐emptive antifungal therapy showed no clear difference in mortality ascribed to fungal infection compared with empirical antifungal therapy (low certainty).

1 finding from 1 review