Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,550 questions · 1,617 findings · 161 reviews · Neonatal

No studies found 238 · 14.7%GRADE not reported 76 · 4.7%Very low 377 · 23.3%Low 567 · 35.1%Moderate 285 · 17.6%High 74 · 4.6%

Targeted individualized vs standard non‐individualized fortification

In‐hospital mortality · promoting growth and development in very low birth weight infants receiving human milk

It is very uncertain whether targeted individualized changes in‐hospital mortality compared with standard non‐individualized fortification (very low certainty).

1 finding from 1 review

Targeted individualized vs standard non‐individualized fortification

Necrotising enterocolitis · promoting growth and development in very low birth weight infants receiving human milk

It is very uncertain whether targeted individualized changes necrotizing enterocolitis compared with standard non‐individualized fortification (very low certainty).

1 finding from 1 review

Targeted individualized vs standard non‐individualized fortification

Culture‐proven late‐onset bacterial sepsis · promoting growth and development in very low birth weight infants receiving human milk

It is very uncertain whether targeted individualized changes culture‐proven late‐onset bacterial sepsis compared with standard non‐individualized fortification (very low certainty).

1 finding from 1 review