evidencegaps
Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

2,973 questions · 3,072 findings · 410 reviews · Headline outcomes only

Sort:Best matchNewestHighest certaintyDownload CSV
No studies found 559 · 18.2%GRADE not reported 143 · 4.7%Very low 654 · 21.3%Low 833 · 27.1%Moderate 683 · 22.2%High 200 · 6.5%

Non‐platinum single‐agent vs non‐platinum combination treatment

Grade 3 and 4 hematological adverse events (AE) ‐ anemia · non‐small cell lung cancer in the elderly population

It is very uncertain whether non‐platinum single‐agent changes grade 3 and 4 hematological adverse events (AE) ‐ anemia compared with non‐platinum combination treatment (very low certainty).

1 finding from 1 review

Non‐platinum single‐agent vs non‐platinum combination treatment

Grade 3 to 4 neutropenia · non‐small cell lung cancer in the elderly population

Non‐platinum single‐agent may leads to higher grade 3 and 4 hematological adverse events (AE) ‐ neutropenia compared with non‐platinum combination treatment (low certainty).

1 finding from 1 review

Non‐platinum single‐agent vs non‐platinum combination treatment

Safety (AE, adverse drug reaction): thrombocytopenia Grades 3 or 4 according to National Cancer Institute · non‐small cell lung cancer in the elderly population

It is very uncertain whether non‐platinum single‐agent changes grade 3 and 4 hematological adverse events (AE) ‐ thrombocytopenia compared with non‐platinum combination treatment (very low certainty).

1 finding from 1 review

Inhaled NO vs placebo or conventional therapy

Mortality before hospital discharge · all infants and children with congenital heart disease having postoperative management of pulmonary hypertension

It is very uncertain whether inhaled nitric oxide changes mortality prior to discharge1 compared with placebo or conventional therapy (very low certainty).

1 finding from 1 review

Non‐invasive ventilation during exercise training vs exercise training alone or exercise training with sham non‐invasive ventilation

Exercise capacity: percentage change constant work rate endurance time Constant work rate cycle endurance test · patients with chronic obstructive pulmonary disease
1 finding from 1 review

Non‐invasive ventilation during exercise training vs exercise training alone or exercise training with sham non‐invasive ventilation

Health‐related quality of life Change in total score of St George Respiratory Questionnaire · patients with chronic obstructive pulmonary disease
1 finding from 1 review

Non‐invasive ventilation during exercise training vs exercise training alone or exercise training with sham non‐invasive ventilation

Physical activity: not measured · patients with chronic obstructive pulmonary disease

The review found no eligible studies for this question.

1 finding from 1 review