Findings

What do systematic reviews say?

3,454 questions · 3,562 findings · 816 reviews · Headline outcomes only

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No studies found 538 · 15.1%GRADE not reported 239 · 6.7%Very low 933 · 26.2%Low 1,041 · 29.2%Moderate 612 · 17.2%High 199 · 5.6%

Colchicine plus standard care vs placebo or usual care

All‐cause mortality assessed up to day 28 · individuals with moderate or severe COVID‐19

1 finding from 1 review

Colchicine for the treatment of COVID‐19 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 11445 participants
Moderate

Colchicine vs placebo or usual care

Adverse events within 28 days · people with SARS‐CoV‐2 infection and asymptomatic or mild disease

1 finding from 1 review

Colchicine for the treatment of COVID‐19 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 4412 participants
Low

Colchicine vs placebo or usual care

Serious adverse events within 28 days · people with SARS‐CoV‐2 infection and asymptomatic or mild disease

1 finding from 1 review

Colchicine for the treatment of COVID‐19 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 4412 participants
Moderate

Colchicine plus standard care vs placebo or usual care

Clinical worsening: need for invasive mechanical ventilation, or death at up to day 28 · individuals with moderate or severe COVID‐19

1 finding from 1 review

Colchicine for the treatment of COVID‐19 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 10916 participants
Moderate

Colchicine plus standard care vs placebo or usual care

Improvement of clinical status: participants discharged alive up to day 28 without clinical deterioration or death · individuals with moderate or severe COVID‐19

1 finding from 1 review

Colchicine for the treatment of COVID‐19 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 11340 participants
Moderate

Colchicine vs placebo or usual care

All‐cause mortality up to day 28 · people with SARS‐CoV‐2 infection and asymptomatic or mild disease

1 finding from 1 review

Colchicine for the treatment of COVID‐19 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 4488 participants
Low

Colchicine vs placebo or usual care

Admission to hospital or death within 28 days · people with SARS‐CoV‐2 infection and asymptomatic or mild disease

1 finding from 1 review

Colchicine for the treatment of COVID‐19 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 4488 participants
Moderate

Stroke ward vs general medical ward

Length of hospital stay · adults with acute stroke

Stroke ward showed no clear difference in length of stay (days) in a hospital or institution (Analysis 2.5) compared with general medical ward (low certainty).

1 finding from 1 review

Organised inpatient (stroke unit) care for stroke: network meta‐analysis 2020 · Cochrane Headline outcomes only
SMD 0.13
10 studies · 2547 participants
Low

Mobile stroke team vs general medical ward

Length of hospital stay · adults with acute stroke

The review found no eligible studies for this question.

1 finding from 1 review

Organised inpatient (stroke unit) care for stroke: network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Mixed rehabilitation ward vs general medical ward

Length of hospital stay · adults with acute stroke

It is very uncertain whether mixed rehabilitation ward changes length of stay (days) in a hospital or institution (Analysis 4.5) compared with general medical ward (very low certainty).

1 finding from 1 review

Organised inpatient (stroke unit) care for stroke: network meta‐analysis 2020 · Cochrane Headline outcomes only
MD 0.08
3 studies · 387 participants
Very low

Organised inpatient (stroke unit) care vs alternative service

Length of hospital stay · adults with acute stroke

Organised inpatient (stroke unit) care showed no clear difference in length of stay (days) in a hospital or institution (Analysis 1.5) compared with alternative service (low certainty).

1 finding from 1 review

Organised inpatient (stroke unit) care for stroke: network meta‐analysis 2020 · Cochrane Headline outcomes only
SMD 0.16
19 studies · 4162 participants
Low

Carbohydrate supplementation vs control

Weight (kg) · preterm infants

1 finding from 1 review

Carbohydrate supplementation of human milk to promote growth in preterm infants 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 75 participants
Very low

Fat supplementation vs control

Rate of weight gain (g/kg/day) · preterm infants

1 finding from 1 review

Fat supplementation of human milk for promoting growth in preterm infants 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 14 participants
Very low

Fat supplementation vs control

Duration of hospital admission (days) · preterm infants

The review found no eligible studies for this question.

1 finding from 1 review

Fat supplementation of human milk for promoting growth in preterm infants 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Protein supplementation vs control

Rate of weight gain (g/kg/day) · preterm infants

1 finding from 1 review

Protein supplementation of human milk for promoting growth in preterm infants 2020 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 101 participants
Low

Protein supplementation vs control

Length of hospital stay · preterm infants

1 finding from 1 review

Protein supplementation of human milk for promoting growth in preterm infants 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Very low

Carotid artery stenting vs endarterectomy

Death or any stroke between randomisation and 30 days after treatment · people with symptomatic carotid stenosis

Carotid artery stenting leads to higher death or any stroke between randomisation and 30 days after treatment compared with endarterectomy (high certainty).

1 finding from 1 review

Carotid artery stenting versus endarterectomy for treatment of carotid artery stenosis 2020 · Cochrane Headline outcomes only
OR 1.7 [1.31, 2.19]
10 studies · 5396 participants
High

Carotid artery stenting vs endarterectomy

Death or any stroke between randomisation and 30 days after treatment or ipsilateral stroke until end of · people with symptomatic carotid stenosis

Carotid artery stenting leads to higher death or any stroke between randomisation and 30 days after… compared with endarterectomy (high certainty).

1 finding from 1 review

Carotid artery stenting versus endarterectomy for treatment of carotid artery stenosis 2020 · Cochrane Headline outcomes only
OR 1.51 [1.24, 1.85]
8 studies · 5080 participants
High

Carotid artery stenting vs endarterectomy

Death or major or disabling stroke between randomisation and 30 days after treatment · people with symptomatic carotid stenosis

Carotid artery stenting showed no clear difference in death or major or disabling stroke between randomisation and 30 days… compared with endarterectomy (high certainty).

1 finding from 1 review

Carotid artery stenting versus endarterectomy for treatment of carotid artery stenosis 2020 · Cochrane Headline outcomes only
OR 1.36 [0.97, 1.91]
7 studies · 4983 participants
High

Carotid artery stenting vs endarterectomy

Death or any stroke or myocardial infarction between randomisation and 30 days after treatment · people with symptomatic carotid stenosis

Carotid artery stenting leads to higher death or any stroke or myocardial infarction between randomisation… compared with endarterectomy (high certainty).

1 finding from 1 review

Carotid artery stenting versus endarterectomy for treatment of carotid artery stenosis 2020 · Cochrane Headline outcomes only
OR 1.43 [1.14, 1.8]
6 studies · 4861 participants
High