What do systematic reviews say?

Exercise vs no exercise

The review found no eligible studies for this question.

• Exercise‐based cardiac rehabilitation for adults after heart valve surgery 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Exercise vs no exercise

It is very uncertain whether exercise changes all‐cause hospitalisation compared with no exercise (very low certainty).

• Exercise‐based cardiac rehabilitation for adults after heart valve surgery 2021 · Cochrane Headline outcomes only
  RR 2.72 [0.11, 65.56]
  1 study · 122 participants
  Very low

Exercise vs no exercise

• Exercise‐based cardiac rehabilitation for adults after heart valve surgery 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 150 participants
  Very low

Exercise vs no exercise

• Exercise‐based cardiac rehabilitation for adults after heart valve surgery 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 150 participants
  Very low

Exercise vs no exercise

• Exercise‐based cardiac rehabilitation for adults after heart valve surgery 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 139 participants
  Very low

Exercise vs no exercise

• Exercise‐based cardiac rehabilitation for adults after heart valve surgery 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 139 participants
  Very low

Intervention not reported

The intervention showed no clear difference in overall survival (Duration of (high certainty).

• Immunotherapy (excluding checkpoint inhibitors) for stage I to III non‐small cell lung cancer treated with surgery or… 2021 · Cochrane Headline outcomes only
  HR 0.94 [0.84, 1.05]
  4 studies · 3848 participants
  High

Intervention not reported

The intervention showed no clear difference in progression‐free survival (moderate certainty).

• Immunotherapy (excluding checkpoint inhibitors) for stage I to III non‐small cell lung cancer treated with surgery or… 2021 · Cochrane Headline outcomes only
  HR 0.94 [0.86, 1.03]
  5 studies · 3861 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in overall survival: 1‐year survival rate  (low certainty).

• Immunotherapy (excluding checkpoint inhibitors) for stage I to III non‐small cell lung cancer treated with surgery or… 2021 · Cochrane Headline outcomes only
  RR 1.02 [0.96, 1.08]
  7 studies · 4420 participants
  Low

Intervention not reported

The intervention showed no clear difference in overall survival: 2‐year survival rate (moderate certainty).

• Immunotherapy (excluding checkpoint inhibitors) for stage I to III non‐small cell lung cancer treated with surgery or… 2021 · Cochrane Headline outcomes only
  RR 1.02 [0.93, 1.12]
  7 studies · 4420 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in overall survival: 3‐year survival rate (moderate certainty).

• Immunotherapy (excluding checkpoint inhibitors) for stage I to III non‐small cell lung cancer treated with surgery or… 2021 · Cochrane Headline outcomes only
  RR 0.99 [0.9, 1.09]
  7 studies · 4420 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in overall survival: 5‐year survival rate (moderate certainty).

• Immunotherapy (excluding checkpoint inhibitors) for stage I to III non‐small cell lung cancer treated with surgery or… 2021 · Cochrane Headline outcomes only
  RR 0.98 [0.86, 1.12]
  7 studies · 4389 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in adverse events: any (Duration of (low certainty).

• Immunotherapy (excluding checkpoint inhibitors) for stage I to III non‐small cell lung cancer treated with surgery or… 2021 · Cochrane Headline outcomes only
  RR 1.12 [0.97, 1.28]
  4 studies · 4126 participants
  Low

Intervention not reported

The intervention showed no clear difference in adverse events: severe, grade > 2 (Duration of (low certainty).

• Immunotherapy (excluding checkpoint inhibitors) for stage I to III non‐small cell lung cancer treated with surgery or… 2021 · Cochrane Headline outcomes only
  RR 1.14 [0.92, 1.4]
  6 studies · 4546 participants
  Low

Early active flexion plus controlled passive exercise regimen vs controlled passive exercise regimen following surgery

• Rehabilitation following surgery for flexor tendon injuries of the hand 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 62 participants
  Very low
• Rehabilitation following surgery for flexor tendon injuries of the hand 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 63 participants
  Very low

Early active flexion plus controlled passive exercise regimen vs controlled passive exercise regimen following surgery

• Rehabilitation following surgery for flexor tendon injuries of the hand 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 63 participants
  Very low
• Rehabilitation following surgery for flexor tendon injuries of the hand 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 63 participants
  Very low

Early active flexion plus controlled passive exercise regimen vs controlled passive exercise regimen following surgery

It is very uncertain whether early active flexion plus controlled passive exercise regimen changes adverse events: participants incurring one or more adverse events compared with early controlled passive exercise regimen (very low certainty).

• Rehabilitation following surgery for flexor tendon injuries of the hand 2021 · Cochrane Headline outcomes only
  RR 0.58 [0.23, 1.44]
  1 study · 69 participants
  Very low

Early active flexion plus controlled passive exercise regimen vs controlled passive exercise regimen following surgery

It is very uncertain whether early active flexion plus controlled passive exercise regimen changes adverse event (tendon rupture) compared with early controlled passive exercise regimen (very low certainty).

• Rehabilitation following surgery for flexor tendon injuries of the hand 2021 · Cochrane Headline outcomes only
  RR 1.73 [0.16, 18.2]
  1 study · 69 participants
  Very low

Sharp‐edged intraocular lens (IOL) vs round‐edged IOL

Sharp‐edged intraocular lens (IOL) showed no clear difference in nd:YAG capsulotomy at one year compared with round‐edged IOL (low certainty).

• Intraocular lens optic edge design for the prevention of posterior capsule opacification after cataract surgery 2021 · Cochrane Headline outcomes only
  OR 0.3 [0.05, 1.74]
  6 studies · 742 participants
  Low

Sharp‐edged intraocular lens (IOL) vs round‐edged IOL

• Intraocular lens optic edge design for the prevention of posterior capsule opacification after cataract surgery 2021 · Cochrane Headline outcomes only
  no estimate extracted
  10 studies · 10 participants
  Moderate