What do systematic reviews say?

Benralizumab 100 mg vs placebo

• Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 1351 participants
  High

Mepolizumab 100 mg vs placebo

• Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 911 participants
  Moderate

Mepolizumab 100 mg vs placebo

• Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 1285 participants
  Moderate

Myofunctional therapy plus nasal washing vs Nasal washing alone

Myofunctional therapy plus nasal washing showed no clear difference in AHI score reduction to below 5 points. compared with nasal washing alone (low certainty).

• Myofunctional therapy (oropharyngeal exercises) for obstructive sleep apnoea 2020 · Cochrane Headline outcomes only
  OR 12.5 [0.84, 186.3]
  1 study · 13 participants
  Low

Bakri balloon tamponade vs haemostatic square suturing to the lower segment of the uterus (intrauterine tamponade versus another mechanical/surgical method)

• Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 13 participants
  Very low

Bakri balloon tamponade vs haemostatic square suturing to the lower segment of the uterus (intrauterine tamponade versus another mechanical/surgical method)

• Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 13 participants
  Very low

Bakri balloon tamponade vs haemostatic square suturing to the lower segment of the uterus (intrauterine tamponade versus another mechanical/surgical method)

• Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 13 participants
  Very low

Bakri balloon tamponade vs haemostatic square suturing to the lower segment of the uterus (intrauterine tamponade versus another mechanical/surgical method)

The review found no eligible studies for this question.

• Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Bakri balloon tamponade vs haemostatic square suturing to the lower segment of the uterus (intrauterine tamponade versus another mechanical/surgical method)

• Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 13 participants
  Very low

Bakri balloon tamponade vs haemostatic square suturing to the lower segment of the uterus (intrauterine tamponade versus another mechanical/surgical method)

It is very uncertain whether bakri balloon tamponade changes blood transfusion (red cell or whole blood) compared with haemostatic square suturing to the lower segment of the uterus… (very low certainty).

• Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
  RR 0.57 [0.14, 2.36]
  1 study · 13 participants
  Very low

Bakri balloon tamponade vs haemostatic square suturing to the lower segment of the uterus (intrauterine tamponade versus another mechanical/surgical method)

• Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 13 participants
  Very low

Digital targeted client communication via mobile devices vs non‐digital targeted client communication (parents of children aged under five years)

Digital targeted client communication via mobile devices showed no clear difference in health behaviour change – hygiene practices (oral health in children… compared with non‐digital targeted client communication (parents of children aged… (low certainty).

• Targeted client communication via mobile devices for improving maternal, neonatal, and child health 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 143 participants
  Low

Digital targeted client communication via mobile devices vs standard skin care or no skin care intervention

Digital targeted client communication via mobile devices showed no clear difference in health status and well‐being ‐ Repeat abortion following an earlier… compared with standard care or no intervention (low certainty).

• Targeted client communication via mobile devices for improving sexual and reproductive health 2020 · Cochrane Headline outcomes only
  RR 0.68 [0.28, 1.66]
  1 study · 328 participants
  Low

Resilience interventions vs controls

• Psychological interventions to foster resilience in healthcare students 2020 · Cochrane Headline outcomes only
  no estimate extracted
  7 studies · 362 participants
  Very low

Resilience interventions vs controls

• Psychological interventions to foster resilience in healthcare students 2020 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 332 participants
  Very low

Resilience interventions vs controls

• Psychological interventions to foster resilience in healthcare students 2020 · Cochrane Headline outcomes only
  no estimate extracted
  7 studies · 420 participants
  Very low

Mucolytic vs placebo

• Mucolytic agents versus placebo for chronic bronchitis or chronic obstructive pulmonary disease 2019 · Cochrane Headline outcomes only
  no estimate extracted
  7 studies · 2721 participants
  Moderate

Copper intrauterine device vs mifepristone (all doses)

Copper intrauterine device may leads to higher specific side effects ‐ lower abdominal pain compared with mifepristone (all doses) (low certainty).

• Interventions for emergency contraception 2019 · Cochrane Headline outcomes only
  RR 73.61 [4.48, 1208.5]
  1 study · 285 participants
  Low

Intervention not reported

It is very uncertain whether the intervention changes participants with any complication: up to 3 months following… (very low certainty).

• Glucocorticosteroids for people with alcoholic hepatitis 2019 · Cochrane Headline outcomes only
  RR 1.04 [0.86, 1.27]
  15 studies · 1861 participants
  Very low

Antibiotic prophylaxis vs placebo, no treatment or surveillance only

Antibiotic prophylaxis showed no clear difference in symptomatic UTI; antibiotics versus placebo in trials with low risk… compared with surveillance or no treatment (moderate certainty).

• Interventions for primary vesicoureteric reflux 2019 · Cochrane Headline outcomes only
  RR 0.85 [0.4, 1.79]
  3 studies · 943 participants
  Moderate