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Evidence found and GRADE certainty

250 questions · 288 findings · 13 reviews · Dental public health and special care

No studies found 73 · 25.3%GRADE not reported 90 · 31.3%Very low 90 · 31.3%Low 29 · 10.1%Moderate 6 · 2.1%High 0 · 0%

Any antimicrobial mouthwash and/or nasal spray (alone or in combination), at any concentration, delivered to healthcare workers, with or without the same intervention given to the patients with COVID-19 vs No treatment or saline or water

Other adverse events (allergy, irritation/burning of nasal, oral or oropharyngeal mucosa, long-term staining of mucous membranes or teeth, accidental ingestion) · Healthcare workers (HCWs) treating patients with suspected or confirmed COVID-19 infection

The review found no eligible studies for this question.

1 finding from 1 review

Laminar air flow with HEPA filter vs Without laminar flow or filter

Reduction in level of contamination in aerosols (CFU per cubic feet/min/patient) using Andersen cascade sampler 20-30 cm from mouth · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether laminar air flow with HEPA filter changes reduction in level of contamination in aerosols (CFU per cubic… compared with without laminar flow or filter (very low certainty).

1 finding from 1 review

Any method, procedure or policy to reduce contaminated aerosols in dental clinics vs Any other method, no treatment or combination of methods

Incidence of infection of dental staff or patients · Dental healthcare providers (dentist, dental surgery assistant, dental hygienist, dental technologist, dental laboratory staff, dental…

The review found no eligible studies for this question.

1 finding from 1 review

Combination system (Isolite) vs Rubber dam + HVE

Reduction in level of contamination in aerosols (CFU) during water spray using high-speed handpiece · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether combination system (Isolite) changes reduction in level of contamination in aerosols (CFU) during water… compared with rubber dam + HVE (very low certainty).

1 finding from 1 review

High-volume evacuation (HVE) vs No HVE

Reduction in level of contamination in aerosols (CFU) during ultrasonic scaling and air polishing at less than 1 foot (~30 cm) from oral cavity (RCTs) · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether high-volume evacuation (HVE) changes reduction in level of contamination in aerosols (CFU) during… compared with no HVE (very low certainty).

1 finding from 1 review

Rubber dam vs No rubber dam

Reduction in level of contamination in aerosols (CFU) during restorative procedures at operator's forehead (RCT) · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether rubber dam changes reduction in level of contamination in aerosols (CFU) during… compared with no rubber dam (very low certainty).

1 finding from 1 review

Chlorhexidine (mouthrinse or gel), as part of oral hygiene care vs placebo or usual care

Duration of systemic antibiotic use · Critically ill patients (adults and children) receiving mechanical ventilation in ICU

Chlorhexidine (mouthrinse or gel), as part of oral hygiene care showed no clear difference in duration of systemic antibiotic use compared with placebo or usual care; GRADE not reported.

1 finding from 1 review

Antimicrobial mouthwash and/or nasal spray (alone or in combination), any concentration, frequency or dosage vs No treatment or saline or water

Changes in microbiome in oral cavity, nasal cavity, oro- or nasopharynx · Patients with suspected or confirmed COVID-19 infection

The review found no eligible studies for this question.

1 finding from 1 review

Rubber dam + HVE vs Cotton roll + HVE

Reduction in level of contamination in aerosols (CFU) during restorative procedures at dental unit light · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether rubber dam + HVE changes reduction in level of contamination in aerosols (CFU) during… compared with cotton roll + HVE (very low certainty).

1 finding from 1 review

Air cleaning system (ACS) vs No air cleaning system

Reduction in level of contamination in aerosols (CFU) during ultrasonic scaling · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether air cleaning system (ACS) changes reduction in level of contamination in aerosols (CFU) during… compared with no air cleaning system (very low certainty).

1 finding from 1 review

Powered toothbrushing (as part of comprehensive oral care) vs Manual toothbrushing

Duration of mechanical ventilation · Critically ill patients receiving mechanical ventilation in ICU

Powered toothbrushing (as part of comprehensive oral care) showed no clear difference in duration of mechanical ventilation compared with manual toothbrushing (standard oral care); GRADE not reported.

1 finding from 1 review

Combination system (Isolite) vs HVE

Reduction in level of contamination in aerosols (CFU) during water spray using high-speed handpiece · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether combination system (Isolite) changes reduction in level of contamination in aerosols (CFU) during water… compared with HVE (very low certainty).

1 finding from 1 review