Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

148 questions · 148 findings · 9 reviews · Kidney and Transplant

No studies found 50 · 33.8%GRADE not reported 1 · 0.7%Very low 43 · 29.1%Low 40 · 27%Moderate 13 · 8.8%High 1 · 0.7%

Uric acid lowering therapies (UAR) vs Placebo, no intervention or usual care (with or without placebo)

Cardiovascular events · people with CKD

Uric acid lowering therapies (UAR) showed no clear difference in cardiovascular events compared with placebo, no treatment or usual care (low certainty).

1 finding from 1 review