Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

210 questions · 213 findings · 37 reviews

No studies found 34 · 16%GRADE not reported 70 · 32.9%Very low 57 · 26.8%Low 38 · 17.8%Moderate 9 · 4.2%High 5 · 2.3%

Hyaluronic acid gel (brushing) vs Chlorhexidine, 0.2% to 2% (solution or gel)

Marginal bleeding · Adults with dental implants and healthy peri-implant soft tissues at baseline

Hyaluronic acid gel (brushing) showed no clear difference in marginal bleeding compared with chlorhexidine gel (brushing); GRADE not reported.

1 finding from 1 review

Amine fluoride/stannous fluoride (AmF/SnF2) mouthwash vs Chlorhexidine mouthwash

Staining index · Adults with dental implants and healthy peri-implant soft tissues at baseline

Amine fluoride/stannous fluoride (AmF/SnF2) mouthwash showed no clear difference in staining index compared with chlorhexidine mouthwash; GRADE not reported.

1 finding from 1 review

Hyaluronic acid gel (brushing) vs Chlorhexidine, 0.2% to 2% (solution or gel)

Plaque · Adults with dental implants and healthy peri-implant soft tissues at baseline

Hyaluronic acid gel (brushing) showed no clear difference in plaque compared with chlorhexidine gel (brushing); GRADE not reported.

1 finding from 1 review

Phosphoric etching (acid) gel vs Mechanical debridement and polishing

Side effects (pain) · Adults with dental implants and healthy peri-implant soft tissues at baseline
1 finding from 1 review

Chlorhexidine solution enclosed in implant inner part vs Normal saline

Plaque · Adults with dental implants and healthy peri-implant soft tissues at baseline

Chlorhexidine solution enclosed in implant inner part showed no clear difference in plaque compared with physiologic (saline) solution; GRADE not reported.

1 finding from 1 review

Amine fluoride/stannous fluoride (AmF/SnF2) mouthwash vs Chlorhexidine mouthwash

Change in taste · Adults with dental implants and healthy peri-implant soft tissues at baseline

Amine fluoride/stannous fluoride (AmF/SnF2) mouthwash led to lower change in taste compared with chlorhexidine mouthwash; GRADE not reported.

1 finding from 1 review

Amine fluoride/stannous fluoride (AmF/SnF2) mouthwash vs Chlorhexidine mouthwash

Implant failure · Adults with dental implants and healthy peri-implant soft tissues at baseline

Amine fluoride/stannous fluoride (AmF/SnF2) mouthwash showed no clear difference in implant failure compared with chlorhexidine mouthwash; GRADE not reported.

1 finding from 1 review

Phosphoric etching (acid) gel vs Mechanical debridement and polishing

Change in probing pocket depth (PPD) · Adults with dental implants and healthy peri-implant soft tissues at baseline

Phosphoric etching (acid) gel showed no clear difference in change in probing pocket depth compared with mechanical debridement and polishing; GRADE not reported.

1 finding from 1 review