What do systematic reviews say?

Dopamine agonist vs placebo or no intervention

It is very uncertain whether dopamine agonist changes any other adverse events compared with placebo/no intervention (very low certainty).

• Dopamine agonists for preventing ovarian hyperstimulation syndrome 2021 · Cochrane Headline outcomes only
  OR 4.54 [1.49, 13.84]
  2 studies · 264 participants
  Very low

Raloxifene vs placebo

The review found no eligible studies for this question.

• Selective oestrogen receptor modulators (SERMs) for endometriosis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Raloxifene vs placebo

It is very uncertain whether raloxifene changes adverse events ‐ pelvic pain compared with placebo (very low certainty).

• Selective oestrogen receptor modulators (SERMs) for endometriosis 2021 · Cochrane Headline outcomes only
  RR 1.25 [0.63, 2.45]
  1 study · 93 participants
  Very low

Raloxifene vs placebo

It is very uncertain whether raloxifene changes adverse events ‐ ovarian cyst compared with placebo (very low certainty).

• Selective oestrogen receptor modulators (SERMs) for endometriosis 2021 · Cochrane Headline outcomes only
  RR 1.57 [0.55, 4.43]
  1 study · 93 participants
  Very low

Raloxifene vs placebo

It is very uncertain whether raloxifene changes adverse events ‐ headache compared with placebo (very low certainty).

• Selective oestrogen receptor modulators (SERMs) for endometriosis 2021 · Cochrane Headline outcomes only
  RR 1.06 [0.48, 2.37]
  1 study · 93 participants
  Very low

Raloxifene vs placebo

It is very uncertain whether raloxifene changes adverse events ‐ migraine compared with placebo (very low certainty).

• Selective oestrogen receptor modulators (SERMs) for endometriosis 2021 · Cochrane Headline outcomes only
  RR 0.73 [0.28, 1.95]
  1 study · 93 participants
  Very low

Raloxifene vs placebo

It is very uncertain whether raloxifene changes adverse events ‐ depression compared with placebo (very low certainty).

• Selective oestrogen receptor modulators (SERMs) for endometriosis 2021 · Cochrane Headline outcomes only
  RR 1.91 [0.62, 5.92]
  1 study · 93 participants
  Very low

Raloxifene vs placebo

It is very uncertain whether raloxifene changes biopsy‐proven recurrence of endometriosis compared with placebo (very low certainty).

• Selective oestrogen receptor modulators (SERMs) for endometriosis 2021 · Cochrane Headline outcomes only
  RR 1.2 [0.66, 6.21]
  1 study · 93 participants
  Very low

Non‐pharmaceutical interventions vs placebo or no intervention

Non‐pharmacological intervention showed no clear difference in live birth compared with no intervention or placebo (low certainty).

• Pharmacological and non‐pharmacological strategies for obese women with subfertility 2021 · Cochrane Headline outcomes only
  OR 0.85 [0.65, 1.12]
  3 studies · 917 participants
  Low

Pharmacological interventions vs placebo or no intervention

It is very uncertain whether pharmacological intervention changes live birth compared with no intervention or placebo (very low certainty).

• Pharmacological and non‐pharmacological strategies for obese women with subfertility 2021 · Cochrane Headline outcomes only
  OR 1.57 [0.44, 5.57]
  1 study · 65 participants
  Very low

Non‐pharmaceutical interventions vs placebo or no intervention

Non‐pharmacological intervention showed no clear difference in ongoing pregnancy compared with no intervention or placebo (low certainty).

• Pharmacological and non‐pharmacological strategies for obese women with subfertility 2021 · Cochrane Headline outcomes only
  OR 0.81 [0.58, 1.13]
  1 study · 564 participants
  Low

Pharmacological interventions vs placebo or no intervention

The review found no eligible studies for this question.

• Pharmacological and non‐pharmacological strategies for obese women with subfertility 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Pharmacological interventions vs placebo or no intervention

It is very uncertain whether pharmacological intervention changes miscarriage compared with no intervention or placebo (very low certainty).

• Pharmacological and non‐pharmacological strategies for obese women with subfertility 2021 · Cochrane Headline outcomes only
  OR 0.5 [0.04, 5.8]
  1 study · 65 participants
  Very low

Pharmacological interventions vs placebo or no intervention

It is very uncertain whether pharmacological intervention changes adverse events (GI) compared with no intervention or placebo (very low certainty).

• Pharmacological and non‐pharmacological strategies for obese women with subfertility 2021 · Cochrane Headline outcomes only
  OR 0.91 [0.32, 2.57]
  1 study · 65 participants
  Very low

Pharmacological interventions vs placebo or no intervention

It is very uncertain whether pharmacological intervention changes clinical pregnancy compared with no intervention or placebo (very low certainty).

• Pharmacological and non‐pharmacological strategies for obese women with subfertility 2021 · Cochrane Headline outcomes only
  OR 2.67 [0.9, 7.93]
  2 studies · 96 participants
  Very low

Pharmacological interventions vs placebo or no intervention

• Pharmacological and non‐pharmacological strategies for obese women with subfertility 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 143 participants
  Very low

Pharmacological interventions vs placebo or no intervention

The review found no eligible studies for this question.

• Pharmacological and non‐pharmacological strategies for obese women with subfertility 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Non‐pharmaceutical interventions vs placebo or no intervention

It is very uncertain whether non‐pharmacological intervention changes miscarriage compared with no intervention or placebo (very low certainty).

• Pharmacological and non‐pharmacological strategies for obese women with subfertility 2021 · Cochrane Headline outcomes only
  OR 1.54 [0.99, 2.39]
  3 studies · 917 participants
  Very low

Non‐pharmaceutical interventions vs placebo or no intervention

Non‐pharmacological intervention showed no clear difference in clinical pregnancy compared with no intervention or placebo (low certainty).

• Pharmacological and non‐pharmacological strategies for obese women with subfertility 2021 · Cochrane Headline outcomes only
  OR 1.06 [0.81, 1.4]
  3 studies · 917 participants
  Low

Non‐pharmaceutical interventions vs placebo or no intervention

• Pharmacological and non‐pharmacological strategies for obese women with subfertility 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 305 participants
  Low