Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

260 questions · 265 findings · 20 reviews · Pregnancy and Childbirth

No studies found 57 · 21.5%GRADE not reported 29 · 10.9%Very low 77 · 29.1%Low 85 · 32.1%Moderate 16 · 6%High 1 · 0.4%

Oral magnesium vs placebo/no treatment

Duration of leg cramps: persisting symptoms after night‐time cramps Always · treating leg cramps in pregnancy

Oral magnesium may leads to lower duration of leg cramps: persisting symptoms after night‐time cramps… compared with placebo/no treatment (low certainty).

1 finding from 1 review

Oral magnesium vs placebo/no treatment

Duration of leg cramps: persisting symptoms after night‐time cramps Sometimes · treating leg cramps in pregnancy

It is very uncertain whether oral magnesium changes duration of leg cramps: persisting symptoms after night‐time cramps… compared with placebo/no treatment (very low certainty).

1 finding from 1 review

Oral magnesium vs placebo/no treatment

Composite outcome: symptoms of leg cramps (intensity and frequency) Partial improvement: decrease in intensity and frequency · treating leg cramps in pregnancy

It is very uncertain whether oral magnesium changes composite outcome: symptoms of leg cramps (intensity and frequency)… compared with placebo/no treatment (very low certainty).

1 finding from 1 review

Dexamethasone: oral vs intramuscular – fetal/neonatal outcomes

Any known death after randomisation (fetal, neonatal, child, child as adult) · women at risk of preterm birth

It is very uncertain whether dexamethasone: oral changes any known death after randomisation (fetal, neonatal, child, child… compared with intramuscular – fetal/neonatal outcomes (very low certainty).

1 finding from 1 review

Dexamethasone: oral vs intramuscular – fetal/neonatal outcomes

Respiratory distress syndrome · women at risk of preterm birth

It is very uncertain whether dexamethasone: oral changes respiratory distress syndrome compared with intramuscular – fetal/neonatal outcomes (very low certainty).

1 finding from 1 review

Dexamethasone: oral vs intramuscular – fetal/neonatal outcomes

Intraventricular haemorrhage · women at risk of preterm birth

It is very uncertain whether dexamethasone: oral changes intraventricular haemorrhage compared with intramuscular – fetal/neonatal outcomes (very low certainty).

1 finding from 1 review

Dexamethasone: oral vs intramuscular – fetal/neonatal outcomes

Necrotising enterocolitis · women at risk of preterm birth

It is very uncertain whether dexamethasone: oral changes necrotising enterocolitis compared with intramuscular – fetal/neonatal outcomes (very low certainty).

1 finding from 1 review