Improved menstrual pattern · adult women with PCOS
1 finding from 1 review
Acne ‐ Visual analogue scale or Clinical acne score · adult women with PCOS
1 finding from 1 review
Body‐mass index (BMI) · adult women with PCOS
1 finding from 1 review
Hirsutism ‐ Clinical F‐G score · adult women with PCOS
1 finding from 1 review
Adverse events ‐ Severe · adult women with PCOS
Metformin showed no clear difference in adverse events ‐ Severe compared with metformin combined with oral contraceptive pill (OCP) (low certainty).
1 finding from 1 review
Minor adverse events · adult women with PCOS
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Resumption of menstrual regularity · women with polycystic ovary syndrome not actively trying to conceive
1 finding from 1 review
no estimate extracted
2016 participants
GRADE not reported
Resumption of spontaneous ovulation · women with polycystic ovary syndrome not actively trying to conceive
1 finding from 1 review
no estimate extracted
2016 participants
GRADE not reported
Clinician's assessment of improvement of hirsutism Ferriman‐Gallwey score Scale from: 0 to 36 · women with polycystic ovary syndrome not actively trying to conceive
1 finding from 1 review
no estimate extracted
2016 participants
GRADE not reported
Improvement in acne severity · women with polycystic ovary syndrome not actively trying to conceive
1 finding from 1 review
no estimate extracted
2016 participants
GRADE not reported
Improvement in testosterone level (nmol/L) after 6 months' treatment · women with polycystic ovary syndrome not actively trying to conceive
1 finding from 1 review
no estimate extracted
2016 participants
GRADE not reported
Adverse effects · women with polycystic ovary syndrome not actively trying to conceive
1 finding from 1 review
no estimate extracted
2016 participants
GRADE not reported
Live birth rate · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Ongoing pregnancy · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation
Progesterone showed no clear difference in ongoing pregnancy rate compared with placebo/no treatment (low certainty).
1 finding from 1 review
Miscarriage per clinical pregnancy · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation
Progesterone showed no clear difference in miscarriage rate per clinical pregnancy compared with placebo/no treatment (low certainty).
1 finding from 1 review
Clinical pregnancy rate · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation
Progesterone may leads to higher clinical pregnancy rate compared with placebo/no treatment (low certainty).
1 finding from 1 review
Multiple pregnancy rate · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation
Progesterone showed no clear difference in multiple pregnancy rate compared with placebo/no treatment (low certainty).
1 finding from 1 review
Adverse events, OHSS, preterm delivery, congenital anomaly · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Live birth or ongoing pregnancy · women with oral (clomiphene citrate or letrozole) stimulation
Progesterone showed no clear difference in live birth rate/ongoing pregnancy compared with placebo/no treatment (low certainty).
1 finding from 1 review
Miscarriage per clinical pregnancy · women with oral (clomiphene citrate or letrozole) stimulation
Progesterone showed no clear difference in miscarriage rate per clinical pregnancy compared with placebo/no treatment (low certainty).
1 finding from 1 review