Findings

What do systematic reviews say?

1,340 questions · 1,512 findings · 205 reviews

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No studies found 317 · 21%GRADE not reported 358 · 23.7%Very low 356 · 23.5%Low 271 · 17.9%Moderate 173 · 11.4%High 37 · 2.4%

Zuclopenthixol dihydrochloride vs chlorprothixene

Mental state: Average endpoint general mental state score (clinically improved) (no data) · schizophrenia

1 finding from 1 review

Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Zuclopenthixol dihydrochloride vs placebo

Adverse effects ‐ important extrapyramidal adverse effects · patients with schizophrenia

It is very uncertain whether zuclopenthixol dihydrochloride changes adverse effects: Clinically important general adverse effect… compared with placebo (very low certainty).

1 finding from 1 review

Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
RR 6.07 [0.86, 43.04]
1 study · 28 participants
Very low

Zuclopenthixol dihydrochloride vs chlorprothixene

Leaving the study early · schizophrenia

It is very uncertain whether zuclopenthixol dihydrochloride changes leaving the study early (any reason) compared with chlorprothixene (very low certainty).

1 finding from 1 review

Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
RR 1 [0.34, 2.93]
1 study · 20 participants
Very low

Zuclopenthixol dihydrochloride vs chlorprothixene

General functioning: Average endpoint general functioning score (clinically improved) (no data) · schizophrenia

1 finding from 1 review

Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Zuclopenthixol dihydrochloride vs CLOZAPINE

Global state: Average endpoint global state score (clinically improved) (no data) · schizophrenia

1 finding from 1 review

Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Zuclopenthixol dihydrochloride vs CLOZAPINE

Adverse effects: Clinically important general adverse effect (no data) · schizophrenia

1 finding from 1 review

Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Zuclopenthixol dihydrochloride vs CLOZAPINE

Death: Suicide and natural causes (no data) · schizophrenia

1 finding from 1 review

Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Zuclopenthixol dihydrochloride vs CLOZAPINE

Length of hospital stay · schizophrenia

1 finding from 1 review

Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Zuclopenthixol dihydrochloride vs CLOZAPINE

Mental state: Average endpoint general mental state score (clinically improved) (no data) · schizophrenia

1 finding from 1 review

Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Zuclopenthixol dihydrochloride vs CLOZAPINE

Leaving the study early · schizophrenia

1 finding from 1 review

Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 407 participants
Low

Zuclopenthixol dihydrochloride vs CLOZAPINE

General functioning: Average endpoint general functioning score (clinically improved) (no data) · schizophrenia

1 finding from 1 review

Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Zuclopenthixol dihydrochloride vs haloperidol

Global state: Average endpoint global state score (clinically improved) (no data) · schizophrenia

1 finding from 1 review

Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 49 participants
Very low

Zuclopenthixol dihydrochloride vs placebo

Death: Suicide and natural causes (no data) · patients with schizophrenia

1 finding from 1 review

Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Zuclopenthixol dihydrochloride vs haloperidol

Adverse effects: Clinically important general adverse effect (no data) · schizophrenia

1 finding from 1 review

Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Zuclopenthixol dihydrochloride vs haloperidol

Death: Suicide and natural causes (no data) · schizophrenia

1 finding from 1 review

Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Zuclopenthixol dihydrochloride vs haloperidol

Length of hospital stay · schizophrenia

1 finding from 1 review

Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Zuclopenthixol dihydrochloride vs haloperidol

Mental state: Average endpoint general mental state score (clinically improved) (no data) · schizophrenia

1 finding from 1 review

Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Zuclopenthixol dihydrochloride vs haloperidol

Leaving the study early · schizophrenia

It is very uncertain whether zuclopenthixol dihydrochloride changes leaving the study early (any reason) compared with haloperidol (very low certainty).

1 finding from 1 review

Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
RR 0.99 [0.72, 1.35]
2 studies · 141 participants
Very low

Zuclopenthixol dihydrochloride vs haloperidol

General functioning: Average endpoint general functioning score (clinically improved) (no data) · schizophrenia

1 finding from 1 review

Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Zuclopenthixol dihydrochloride vs OTHER ANTIPSYCHOTIC: f. PERPHENAZINE

Global state: Average endpoint global state score (clinically improved) (no data) · schizophrenia

1 finding from 1 review

Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported