Findings

What do systematic reviews say?

237 questions · 238 findings · 41 reviews · Musculoskeletal

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No studies found 43 · 18.1%GRADE not reported 7 · 2.9%Very low 48 · 20.2%Low 89 · 37.4%Moderate 39 · 16.4%High 12 · 5%

Resistance training vs aerobic exercise training

Pain Visual analog scale Scale from 0 to 100 (lower is better) · patients with fibromyalgia

1 finding from 1 review

Resistance exercise training for fibromyalgia 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 86 participants
Low

Resistance training vs aerobic exercise training

Tender points Tender point score and number of tender points · patients with fibromyalgia

1 finding from 1 review

Resistance exercise training for fibromyalgia 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 86 participants
Low

Resistance training vs flexibility exercise

Multidimensional function FIQ Total Score. Scale 0‐100 (lower scores indicate greater health) · patients with fibromyalgia

1 finding from 1 review

Resistance exercise training for fibromyalgia 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 56 participants
Low

Resistance training vs flexibility exercise

Participant‐reported pain intensity VAS (0‐10, lower score = less pain) · patients with fibromyalgia

1 finding from 1 review

Resistance exercise training for fibromyalgia 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 56 participants
Low

Resistance training vs flexibility exercise

Tender points Tender point score and number of tender points · patients with fibromyalgia

1 finding from 1 review

Resistance exercise training for fibromyalgia 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 56 participants
Low

Resistance training vs control

Physical function · patients with fibromyalgia

1 finding from 1 review

Resistance exercise training for fibromyalgia 2013 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 107 participants
Low

Resistance training vs control

Pain Visual analog scale Scale from 0 to 100 (lower is better) · patients with fibromyalgia

1 finding from 1 review

Resistance exercise training for fibromyalgia 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 81 participants
Low

Resistance training vs control

Tender points Tender point score and number of tender points · patients with fibromyalgia

1 finding from 1 review

Resistance exercise training for fibromyalgia 2013 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 107 participants
Low

Resistance training vs aerobic exercise training

Multidimensional function FIQ Total Score. Scale 0‐100 (lower scores indicate greater health) · patients with fibromyalgia

1 finding from 1 review

Resistance exercise training for fibromyalgia 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Low

Intervention not reported

Achievement of low disease state (DAS 28) ‐ not measured · patients with Rheumatoid arthritis

The review found no eligible studies for this question.

1 finding from 1 review

Herbal therapy for treating rheumatoid arthritis 2011 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Achievement of low disease state (DAS 28) ‐ not measured · patients with treating rheumatoid arthritis

The review found no eligible studies for this question.

1 finding from 1 review

Herbal therapy for treating rheumatoid arthritis 2011 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

DAS (low or remission) · patients with rheumatoid arthritis

1 finding from 1 review

Balance training (proprioceptive training) for patients with rheumatoid arthritis 2010 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Total Shoulder Arthroplasty vs hemiarthroplasty

Pain Visual analog scale Scale from 0 to 100 (lower is better) · patients with Shoulder osteoarthritis

1 finding from 1 review

Surgery for shoulder osteoarthritis 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 41 participants
Low

Intervention not reported

Number of patients experiencing any serious adverse event Median follow ‐up: 4 weeks · patients with osteoarthritis

The intervention showed no clear difference in number of patients experiencing any serious adverse event Median… (low certainty).

1 finding from 1 review

Transcutaneous electrostimulation for osteoarthritis of the knee 2009 · Cochrane Headline outcomes only
RR 0.33 [0.02, 7.32]
4 studies · 195 participants
Low

Abatacept (2 and 10mg/kg) + DMARDs/biologic vs placebo + DMARDs/biologic

Achievement of low disease activity state (DAS 28 less than 3.2, scale 0‐10) · patients with rheumatoid arthritis

Abatacept (2 and 10mg/kg) + DMARDs/biologic probably leads to higher achievement of low disease activity state (DAS 28 less than 3.2,… compared with placebo + DMARDs/biologic (moderate certainty).

1 finding from 1 review

Abatacept for rheumatoid arthritis 2009 · Cochrane Headline outcomes only
RR 4.33 [2.84, 6.59]
1 study · 638 participants
Moderate

Any cold therapy vs no cold therapy following total knee replacement

Blood lossTime point: mean 48 hours, range 1 to 13 days. Higher blood loss indicates a worse outcome. · people undergoing total knee replacement

1 finding from 1 review

Cryotherapy following total knee replacement 2023 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 956 participants
Low

Any cold therapy vs no cold therapy following total knee replacement

Pain at post‐operative day 2Scale from 0 (best) to 10 (worst). · people undergoing total knee replacement

1 finding from 1 review

Cryotherapy following total knee replacement 2023 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 530 participants
Low

Any cold therapy vs no cold therapy following total knee replacement

Transfusion rate · people undergoing total knee replacement

It is very uncertain whether any cold therapy changes transfusion rate compared with no cold therapy following total knee replacement (very low certainty).

1 finding from 1 review

Cryotherapy following total knee replacement 2023 · Cochrane Headline outcomes only
RR 2.13 [0.04, 109.63]
2 studies · 91 participants
Very low

Any cold therapy vs no cold therapy following total knee replacement

Range of motion at discharge Scale from: 0 to 125. · people undergoing total knee replacement

1 finding from 1 review

Cryotherapy following total knee replacement 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 174 participants
Low

Any cold therapy vs no cold therapy following total knee replacement

Function Standardised scale with positive score indicating a better outcome. Scale from 0 (worst) to 100 (best). · people undergoing total knee replacement

1 finding from 1 review

Cryotherapy following total knee replacement 2023 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 296 participants
Very low