Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

305 questions · 305 findings · 37 reviews

No studies found 75 · 24.6%GRADE not reported 22 · 7.2%Very low 57 · 18.7%Low 97 · 31.8%Moderate 46 · 15.1%High 8 · 2.6%

Oral misoprostol vs vaginal misoprostol

Admission to neonatal intensive care unit · women in the third trimester for induction of labour.

Oral misoprostol showed no clear difference in admission to neonatal intensive care unit compared with vaginal misoprostol (moderate certainty).

1 finding from 1 review

Oral misoprostol vs intravenous (IV) oxytocin

Uterine hyperstimulation with fetal heart rate changes · women in the third trimester for induction of labour.

It is very uncertain whether oral misoprostol changes uterine hyperstimulation with fetal heart rate changes compared with intravenous oxytocin (very low certainty).

1 finding from 1 review

Oral misoprostol vs intravenous (IV) oxytocin

Uterine hyperstimulation without fetal heart rate changes · women in the third trimester for induction of labour.

It is very uncertain whether oral misoprostol changes uterine hyperstimulation without fetal heart rate changes compared with intravenous oxytocin (very low certainty).

1 finding from 1 review

Oral misoprostol vs placebo/no treatment

Uterine hyperstimulation with fetal heart rate changes · women with ruptured membranes in the third trimester for induction of labour.

It is very uncertain whether oral misoprostol changes uterine hyperstimulation with fetal heart rate changes compared with placebo/no treatment (very low certainty).

1 finding from 1 review

Oral misoprostol vs mechanical methods

Uterine hyperstimulation with fetal heart rate changes · women in the third trimester for induction of labour.

Oral misoprostol showed no clear difference in uterine hyperstimulation with fetal heart rate changes compared with mechanical methods (low certainty).

1 finding from 1 review

Oral misoprostol vs mechanical methods

Uterine hyperstimulation without fetal heart rate changes · women in the third trimester for induction of labour.

It is very uncertain whether oral misoprostol changes uterine hyperstimulation without fetal heart rate changes compared with mechanical methods (very low certainty).

1 finding from 1 review

Oral misoprostol one‐ to two‐hourly vs oral misoprostol four‐ to six‐hourly

Vaginal birth within 24 hours · women in the third trimester for induction of labour with intact membranes

It is very uncertain whether oral misoprostol one‐ to two‐hourly changes vaginal birth within 24 hours compared with oral misoprostol four‐ to six‐hourly (very low certainty).

1 finding from 1 review

Oral misoprostol one‐ to two‐hourly vs oral misoprostol four‐ to six‐hourly

Caesarean section · women in the third trimester for induction of labour with intact membranes

It is very uncertain whether oral misoprostol one‐ to two‐hourly changes caesarean section compared with oral misoprostol four‐ to six‐hourly (very low certainty).

1 finding from 1 review