Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

161 questions · 189 findings · 10 reviews · Orthodontics

No studies found 77 · 40.7%GRADE not reported 61 · 32.3%Very low 35 · 18.5%Low 13 · 6.9%Moderate 3 · 1.6%High 0 · 0%

Experimental chewing adjuncts (bite wafers or chewing gum) vs No chewing gum, placebo, or control (no adjunct)

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adolescents/teenagers undergoing orthodontic treatment

Experimental chewing adjuncts (bite wafers or chewing gum) showed no clear difference in patient‐reported pain intensity or pain relief (VAS, NRS or… compared with no chewing gum, placebo, or control (no adjunct); GRADE not reported.

5 findings from 1 review
Show 2 more findings

Post‐treatment communication (text messaging) vs No communication (no text message)

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
1 finding from 1 review

Vibratory stimulation (vibratory adjuncts) vs No vibration or placebo vibration

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adolescents and adults undergoing orthodontic treatment

Vibratory stimulation (vibratory adjuncts) showed no clear difference in patient‐reported pain intensity or pain relief (VAS, NRS or… compared with no vibration or placebo vibration; GRADE not reported.

5 findings from 1 review
Show 2 more findings

Brain wave music (BWM) vs No special instructions (control)

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adults undergoing orthodontic treatment

Brain wave music (BWM) showed no clear difference in patient‐reported pain intensity or pain relief (VAS, NRS or… compared with no special instructions (control); GRADE not reported.

3 findings from 1 review

Psychological intervention: structured telephone call (verbal follow‐up and reassurance) vs placebo or no intervention

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)

The review found no eligible studies for this question.

1 finding from 1 review

Vibratory stimulation (vibratory adjuncts) vs No vibration or placebo vibration

Dose/intensity and frequency of pain relief needed (analgesic/rescue medication use) · Adolescents and adults undergoing orthodontic treatment

Vibratory stimulation (vibratory adjuncts) led to lower dose/intensity and frequency of pain relief needed (analgesic/rescue… compared with no vibration or placebo vibration; GRADE not reported.

1 finding from 1 review

Experimental chewing adjuncts (bite wafers or chewing gum) vs No chewing gum, placebo, or control (no adjunct)

Quality of life or patient satisfaction · Adolescents/teenagers undergoing orthodontic treatment

Experimental chewing adjuncts (bite wafers or chewing gum) led to lower quality of life or patient satisfaction compared with no chewing gum, placebo, or control (no adjunct); GRADE not reported.

1 finding from 1 review

Experimental chewing adjuncts (bite wafers or chewing gum) vs No chewing gum, placebo, or control (no adjunct)

Dose/intensity and frequency of pain relief needed (analgesic/rescue medication use) · Adolescents/teenagers undergoing orthodontic treatment
1 finding from 1 review

Orthodontic appliances (palatal crib) vs no treatment

Occlusion (change in maxillary arch length, short term) · Children with a non-nutritive sucking habit (digit or pacifier)
1 finding from 1 review

Orthodontic appliances (palatal crib) vs no treatment

Adverse events · Children with a non-nutritive sucking habit (digit or pacifier)
1 finding from 1 review

Orthodontic appliances (palatal crib) vs no treatment

Sucking cessation (long term) · Children with a non-nutritive sucking habit (digit or pacifier)

Orthodontic appliances (palatal crib) led to higher sucking cessation (long term) compared with no treatment; GRADE not reported.

1 finding from 1 review

Repositioning of ankylosed teeth after osteotomy followed or not by distraction osteogenesis, or after luxation vs Conventional orthodontic treatment or follow-up with no specific treatment for ankylosis

Outcome not reported · Any patient with ankylosis and displacement of permanent front teeth diagnosed by clinical and radiographic assessment, with or without…

The review found no eligible studies for this question.

1 finding from 1 review