Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

166 questions · 194 findings · 13 reviews · Orthodontics

No studies found 81 · 41.8%GRADE not reported 62 · 32%Very low 35 · 18%Low 13 · 6.7%Moderate 3 · 1.5%High 0 · 0%

CBT vs No special instructions (control)

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adults undergoing orthodontic treatment

Cognitive behavioural therapy (CBT) led to lower patient‐reported pain intensity or pain relief (VAS, NRS or… compared with no special instructions (control); GRADE not reported.

3 findings from 1 review

Low‐level laser therapy vs Placebo (or no irradiation)

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adolescents and adults undergoing orthodontic treatment

Low‐level laser therapy (LLLT) showed no clear difference in patient‐reported pain intensity or pain relief (VAS, NRS or… compared with placebo (or no irradiation); GRADE not reported.

5 findings from 1 review
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Experimental chewing adjuncts (bite wafers or chewing gum) vs No chewing gum, placebo, or control (no adjunct)

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adolescents/teenagers undergoing orthodontic treatment

Experimental chewing adjuncts (bite wafers or chewing gum) showed no clear difference in patient‐reported pain intensity or pain relief (VAS, NRS or… compared with no chewing gum, placebo, or control (no adjunct); GRADE not reported.

5 findings from 1 review
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Post‐treatment communication (text messaging) vs No communication (no text message)

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
1 finding from 1 review

Vibratory stimulation (vibratory adjuncts) vs No vibration or placebo vibration

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adolescents and adults undergoing orthodontic treatment

Vibratory stimulation (vibratory adjuncts) showed no clear difference in patient‐reported pain intensity or pain relief (VAS, NRS or… compared with no vibration or placebo vibration; GRADE not reported.

5 findings from 1 review
Show 2 more findings