Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

313 questions · 352 findings · 23 reviews · Drugs and Alcohol

No studies found 16 · 4.5%GRADE not reported 34 · 9.7%Very low 113 · 32.1%Low 117 · 33.2%Moderate 57 · 16.2%High 15 · 4.3%

Tricyclic antidepressants vs placebo

Benzodiazepine discontinuation, end of intervention · adults who withdraw from chronic benzodiazepine use

It is very uncertain whether tricyclic antidepressants changes benzodiazepine discontinuation, end of intervention compared with placebo (very low certainty).

1 finding from 1 review

Magnesium aspartate vs placebo

Benzodiazepine discontinuation, end of intervention · adults who withdraw from chronic benzodiazepine use

It is very uncertain whether magnesium aspartate changes benzodiazepine discontinuation, end of intervention compared with placebo (very low certainty).

1 finding from 1 review