Patient‐reported ability to have intercourse · men with Peyronie's disease (palpable plaque or pain)
It is very uncertain whether injectional verapamil changes patient‐reported ability to have intercourse compared with saline (short‐term) (very low certainty).
1 finding from 1 review
Quality of life · men with Peyronie's disease (palpable plaque or pain)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Treatment‐related adverse effects · men with Peyronie's disease (palpable plaque or pain)
1 finding from 1 review
Degree of penile curvature · men with Peyronie's disease (palpable plaque or pain)
1 finding from 1 review
Treatment discontinuation · men with Peyronie's disease (palpable plaque or pain)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Complete release of vitreous adhesion · people with symptomatic vitreomacular adhesion
Ocriplasmin injection leads to higher complete release of vitreous adhesion compared with control (high certainty).
1 finding from 1 review
RR 3.46 [2, 6]
Studies not reported
High
Closure of macular hole · people with symptomatic vitreomacular adhesion
Ocriplasmin injection leads to higher closure of macular hole compared with control (high certainty).
1 finding from 1 review
RR 2.87 [1.5, 5.51]
Studies not reported
High
Complete posterior vitreous detachment · people with symptomatic vitreomacular adhesion
Ocriplasmin injection leads to higher complete posterior vitreous detachment compared with control (high certainty).
1 finding from 1 review
RR 2.94 [1.39, 6.24]
Studies not reported
High
3‐line or greater improvement in best‐corrected visual acuity · people with symptomatic vitreomacular adhesion
Ocriplasmin injection probably leads to higher 3‐line or greater improvement in best‐corrected visual acuity compared with control (moderate certainty).
1 finding from 1 review
RR 1.95 [1.07, 3.53]
Studies not reported
Moderate
Requirement for vitrectomy · people with symptomatic vitreomacular adhesion
Ocriplasmin injection probably leads to lower requirement for vitrectomy compared with control (moderate certainty).
1 finding from 1 review
RR 0.67 [0.5, 0.91]
Studies not reported
Moderate
Mean change in validated visual function questionnaire score from baseline Score ranges from 0 to 100, higher scores are better visual function · people with symptomatic vitreomacular adhesion
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Adverse events (ocular problems) · people with symptomatic vitreomacular adhesion
Ocriplasmin injection probably leads to higher any ocular adverse event compared with control (moderate certainty).
1 finding from 1 review
RR 1.22 [1.09, 1.37]
Studies not reported
Moderate
Outcomes ( · men with chronic Peyronie's disease (plaques without calcification)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Patient‐reported ability to have intercourse · men with chronic Peyronie's disease (plaques without calcification)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life · men with chronic Peyronie's disease (plaques without calcification)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Treatment‐related adverse effects · men with chronic Peyronie's disease (plaques without calcification)
It is very uncertain whether injectional nicardipine changes treatment‐related adverse effects compared with saline (very low certainty).
1 finding from 1 review
Degree of penile curvature · men with chronic Peyronie's disease (plaques without calcification)
1 finding from 1 review
Treatment discontinuation · men with chronic Peyronie's disease (plaques without calcification)
It is very uncertain whether injectional nicardipine changes discontinuation from treatment compared with saline (very low certainty).
1 finding from 1 review
Outcomes ( · men with Peyronie's disease (diagnosis of disease: at least 12 months, penile curvature: at least 30 degrees)
The review found no eligible studies for this question.
2 findings from 1 review
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
Patient‐reported ability to have intercourse · men with Peyronie's disease (diagnosis of disease: at least 12 months, penile curvature: at least 30 degrees)
The review found no eligible studies for this question.
2 findings from 1 review
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found