Findings

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Evidence found and GRADE certainty

131 questions · 215 findings · 26 reviews · All outcomes

No studies found 0 · 0%GRADE not reported 190 · 88.4%Very low 3 · 1.4%Low 8 · 3.7%Moderate 7 · 3.3%High 7 · 3.3%

11-16 remaining teeth vs 25-32 remaining teeth

Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies

In prospective cohorts, adults with 11-16 teeth had a higher cumulative incidence of ACVD-related events than adults with 25-32 teeth (RR 2.27, 95% CI 1.55 to 3.32; 4 cohort studies, I2=87%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).

1 finding from 1 review

Edentulous (0 remaining teeth) vs 1-32 remaining teeth

All-cause mortality (ACM) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies

In prospective cohorts, the multivariable-adjusted HR for all-cause mortality in edentulous adults (0 teeth) vs adults with 1-32 teeth was 1.30 (95% CI 1.21 to 1.40; 7 studies, I2=20%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).

4 findings from 1 review
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17-24 remaining teeth vs 25-32 remaining teeth

Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies

In prospective cohorts, adults with 17-24 teeth had a higher cumulative incidence of ACVD-related events than adults with 25-32 teeth (RR 1.73, 95% CI 1.22 to 2.45; 4 cohort studies, I2=87%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).

1 finding from 1 review

0-19 remaining teeth vs 20-32 remaining teeth

All-cause mortality (ACM) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies

In prospective cohorts, the crude HR for all-cause mortality in adults with 0-19 teeth vs adults with 20-32 teeth was 2.47 (95% CI 2.40 to 2.54; 2 studies, I2=0%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).

4 findings from 1 review
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1-19 remaining teeth vs 20-32 remaining teeth

All-cause mortality (ACM) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies

In prospective cohorts, adults with 1-19 teeth had a higher cumulative incidence of all-cause mortality than adults with 20-32 teeth (RR 1.76, 95% CI 1.41 to 2.19; 8 cohort studies, I2=94%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).

1 finding from 1 review

Edentulous (0 remaining teeth) vs 1-32 remaining teeth

Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies

In prospective cohorts, the multivariable-adjusted HR for ACVD-related events in edentulous adults (0 teeth) vs adults with 1-32 teeth was 1.21 (95% CI 1.07 to 1.36; 5 studies, I2=35%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).

4 findings from 1 review
Show 1 more finding

0-19 remaining teeth vs 20-32 remaining teeth

Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies

In prospective cohorts, the crude HR for ACVD-related events in adults with 0-19 teeth vs adults with 20-32 teeth was 2.27 (95% CI 1.50 to 3.43; 1 study, I2 not applicable (single study)); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).

4 findings from 1 review
Show 1 more finding

Edentulous (0 remaining teeth) vs 20-32 remaining teeth

Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies

In prospective cohorts, edentulous adults (0 teeth) had a higher cumulative incidence of ACVD-related events than adults with 20-32 teeth (RR 2.65, 95% CI 1.77 to 3.98; 2 cohort studies, I2=60%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).

1 finding from 1 review

1-19 remaining teeth vs 20-32 remaining teeth

Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies

In prospective cohorts, adults with 1-19 teeth had a higher cumulative incidence of ACVD-related events than adults with 20-32 teeth (RR 1.69, 95% CI 1.13 to 2.53; 2 cohort studies, I2=60%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).

1 finding from 1 review

Edentulous (0 remaining teeth) vs 20-32 remaining teeth

All-cause mortality (ACM) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies

In prospective cohorts, edentulous adults (0 teeth) had a higher cumulative incidence of all-cause mortality than adults with 20-32 teeth (RR 2.27, 95% CI 1.82 to 2.83; 8 cohort studies, I2=94%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).

1 finding from 1 review

0-10 remaining teeth vs 25-32 remaining teeth

Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies

In prospective cohorts, adults with 0-10 teeth had a higher cumulative incidence of ACVD-related events than adults with 25-32 teeth (RR 2.65, 95% CI 1.84 to 3.81; 4 cohort studies, I2=87%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).

1 finding from 1 review