Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

128 questions · 133 findings · 20 reviews · Neonatal

No studies found 34 · 25.6%GRADE not reported 5 · 3.8%Very low 36 · 27.1%Low 36 · 27.1%Moderate 22 · 16.5%High 0 · 0%

Prophylactic CPAP vs mechanical ventilation

Bronchopulmonary dysplasia at 36 weeks defined as oxygen dependency at 36 weeks postmenstrual age · preterm infants

Prophylactic CPAP probably leads to lower bronchopulmonary dysplasia at 36 weeks defined as oxygen dependency… compared with mechanical ventilation (moderate certainty).

1 finding from 1 review

Continuous positive airway pressure (CPAP) vs supplemental oxygen

Treatment failure (death or use of additional ventilatory support) · preterm infants with respiratory distress for initial respiratory support

It is very uncertain whether CPAP changes treatment failure (death or use of additional ventilatory support) compared with supplemental oxygen (very low certainty).

1 finding from 1 review

Continuous positive airway pressure (CPAP) vs supplemental oxygen

Bronchopulmonary dysplasia at 28 days · preterm infants with respiratory distress for initial respiratory support

It is very uncertain whether CPAP changes bronchopulmonary dysplasia (oxygen dependency at 28 days) compared with supplemental oxygen (very low certainty).

1 finding from 1 review